1. R65 Symptoms and signs specifically associated with systemic inflammation and infection

    1. R65.1 Systemic inflammatory response syndrome (SIRS) of non-infectious origin

      1. R65.10 Systemic inflammatory response syndrome (SIRS) of non-infectious origin without acute organ dysfunction

        Inclusion term(s):

        • Systemic inflammatory response syndrome (SIRS) NOS
      2. R65.11 Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunction

    2. R65.2 Severe sepsis

      Inclusion term(s):

      • Infection with associated acute organ dysfunction
      • Sepsis with acute organ dysfunction
      • Sepsis with multiple organ dysfunction
      • Systemic inflammatory response syndrome due to infectious process with acute organ dysfunction
      1. R65.20 Severe sepsis without septic shock

        Inclusion term(s):

        • Severe sepsis NOS
      2. R65.21 Severe sepsis with septic shock

Abbreviations used here:

NEC Not elsewhere classifiable
This abbreviation in the Tabular List represents “other specified”. When a specific code is not available for a condition, the Tabular List includes an NEC entry under a code to identify the code as the “other specified” code.

NOS Not otherwise specified
This abbreviation is the equivalent of unspecified.