The drug giving rise to the adverse effect should be identified by use of codes from categories T36-T50 with fifth or sixth character 5.

Use additional code(s) to specify:
manifestations of poisoning
underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
underdosing of medication regimen (Z91.12-, Z91.13-)

Code first  , for adverse effects, the nature of the adverse effect, such as:
  adverse effect NOS (T88.7)
  aspirin gastritis (K29.-)
  blood disorders (D56-D76)
  contact dermatitis (L23-L25)
  dermatitis due to substances taken internally (L27.-)
  nephropathy (N14.0-N14.2)

Includes:

  • adverse effect of correct substance properly administered
  • poisoning by overdose of substance
  • poisoning by wrong substance given or taken in error
  • underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed

Excludes1

  • toxic reaction to local anesthesia in pregnancy (O29.3-)

Excludes2

  • abuse and dependence of psychoactive substances (F10-F19)
  • abuse of non-dependence-producing substances (F55.-)
  • immunodeficiency due to drugs (D84.821)
  • drug reaction and poisoning affecting newborn (P00-P96)
  • pathological drug intoxication (inebriation) (F10-F19)
  1. T41 Poisoning by, adverse effect of and underdosing of anesthetics and therapeutic gases

    1. T41.0 Poisoning by, adverse effect of and underdosing of inhaled anesthetics

      1. T41.0X Poisoning by, adverse effect of and underdosing of inhaled anesthetics

        • T41.0X1 Poisoning by inhaled anesthetics, accidental (unintentional)

          Inclusion term(s):

          • Poisoning by inhaled anesthetics NOS
        • T41.0X2 Poisoning by inhaled anesthetics, intentional self-harm
        • T41.0X3 Poisoning by inhaled anesthetics, assault
        • T41.0X4 Poisoning by inhaled anesthetics, undetermined
        • T41.0X5 Adverse effect of inhaled anesthetics
        • T41.0X6 Underdosing of inhaled anesthetics
    2. T41.1 Poisoning by, adverse effect of and underdosing of intravenous anesthetics

      Inclusion term(s):

      • Poisoning by, adverse effect of and underdosing of thiobarbiturates
      1. T41.1X Poisoning by, adverse effect of and underdosing of intravenous anesthetics

        • T41.1X1 Poisoning by intravenous anesthetics, accidental (unintentional)

          Inclusion term(s):

          • Poisoning by intravenous anesthetics NOS
        • T41.1X2 Poisoning by intravenous anesthetics, intentional self-harm
        • T41.1X3 Poisoning by intravenous anesthetics, assault
        • T41.1X4 Poisoning by intravenous anesthetics, undetermined
        • T41.1X5 Adverse effect of intravenous anesthetics
        • T41.1X6 Underdosing of intravenous anesthetics
    3. T41.2 Poisoning by, adverse effect of and underdosing of other and unspecified general anesthetics

      1. T41.20 Poisoning by, adverse effect of and underdosing of unspecified general anesthetics

        • T41.201 Poisoning by unspecified general anesthetics, accidental (unintentional)

          Inclusion term(s):

          • Poisoning by general anesthetics NOS
        • T41.202 Poisoning by unspecified general anesthetics, intentional self-harm
        • T41.203 Poisoning by unspecified general anesthetics, assault
        • T41.204 Poisoning by unspecified general anesthetics, undetermined
        • T41.205 Adverse effect of unspecified general anesthetics
        • T41.206 Underdosing of unspecified general anesthetics
      2. T41.29 Poisoning by, adverse effect of and underdosing of other general anesthetics

        • T41.291 Poisoning by other general anesthetics, accidental (unintentional)

          Inclusion term(s):

          • Poisoning by other general anesthetics NOS
        • T41.292 Poisoning by other general anesthetics, intentional self-harm
        • T41.293 Poisoning by other general anesthetics, assault
        • T41.294 Poisoning by other general anesthetics, undetermined
        • T41.295 Adverse effect of other general anesthetics
        • T41.296 Underdosing of other general anesthetics
    4. T41.3 Poisoning by, adverse effect of and underdosing of local anesthetics

      Inclusion term(s):

      • Cocaine (topical)
      1. T41.3X Poisoning by, adverse effect of and underdosing of local anesthetics

        • T41.3X1 Poisoning by local anesthetics, accidental (unintentional)

          Inclusion term(s):

          • Poisoning by local anesthetics NOS
        • T41.3X2 Poisoning by local anesthetics, intentional self-harm
        • T41.3X3 Poisoning by local anesthetics, assault
        • T41.3X4 Poisoning by local anesthetics, undetermined
        • T41.3X5 Adverse effect of local anesthetics
        • T41.3X6 Underdosing of local anesthetics
    5. T41.4 Poisoning by, adverse effect of and underdosing of unspecified anesthetic

      1. T41.41 Poisoning by unspecified anesthetic, accidental (unintentional)

        Inclusion term(s):

        • Poisoning by anesthetic NOS
      2. T41.42 Poisoning by unspecified anesthetic, intentional self-harm

      3. T41.43 Poisoning by unspecified anesthetic, assault

      4. T41.44 Poisoning by unspecified anesthetic, undetermined

      5. T41.45 Adverse effect of unspecified anesthetic

      6. T41.46 Underdosing of unspecified anesthetics

    6. T41.5 Poisoning by, adverse effect of and underdosing of therapeutic gases

      1. T41.5X Poisoning by, adverse effect of and underdosing of therapeutic gases

        • T41.5X1 Poisoning by therapeutic gases, accidental (unintentional)

          Inclusion term(s):

          • Poisoning by therapeutic gases NOS
        • T41.5X2 Poisoning by therapeutic gases, intentional self-harm
        • T41.5X3 Poisoning by therapeutic gases, assault
        • T41.5X4 Poisoning by therapeutic gases, undetermined
        • T41.5X5 Adverse effect of therapeutic gases
        • T41.5X6 Underdosing of therapeutic gases
Abbreviations used here:

NEC Not elsewhere classifiable
This abbreviation in the Tabular List represents “other specified”. When a specific code is not available for a condition, the Tabular List includes an NEC entry under a code to identify the code as the “other specified” code.

NOS Not otherwise specified
This abbreviation is the equivalent of unspecified.