The drug giving rise to the adverse effect should be identified by use of codes from categories T36-T50 with fifth or sixth character 5.

Use additional code(s) to specify:
manifestations of poisoning
underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
underdosing of medication regimen (Z91.12-, Z91.13-)

Code first  , for adverse effects, the nature of the adverse effect, such as:
  adverse effect NOS (T88.7)
  aspirin gastritis (K29.-)
  blood disorders (D56-D76)
  contact dermatitis (L23-L25)
  dermatitis due to substances taken internally (L27.-)
  nephropathy (N14.0-N14.2)

Includes:

  • adverse effect of correct substance properly administered
  • poisoning by overdose of substance
  • poisoning by wrong substance given or taken in error
  • underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed

Excludes1

  • toxic reaction to local anesthesia in pregnancy (O29.3-)

Excludes2

  • abuse and dependence of psychoactive substances (F10-F19)
  • abuse of non-dependence-producing substances (F55.-)
  • immunodeficiency due to drugs (D84.821)
  • drug reaction and poisoning affecting newborn (P00-P96)
  • pathological drug intoxication (inebriation) (F10-F19)
  1. T38 Poisoning by, adverse effect of and underdosing of hormones and their synthetic substitutes and antagonists, not elsewhere classified

    Excludes1

    • mineralocorticoids and their antagonists (T50.0-)
    • oxytocic hormones (T48.0-)
    • parathyroid hormones and derivatives (T50.9-)

    The appropriate 7th character is to be added to each code from category T38

    • A - initial encounter
    • D - subsequent encounter
    • S - sequela
    1. T38.0 Poisoning by, adverse effect of and underdosing of glucocorticoids and synthetic analogues

      1. T38.0X Poisoning by, adverse effect of and underdosing of glucocorticoids and synthetic analogues

        • T38.0X1 Poisoning by glucocorticoids and synthetic analogues, accidental (unintentional)

          Inclusion term(s):

          • Poisoning by glucocorticoids and synthetic analogues NOS
        • T38.0X2 Poisoning by glucocorticoids and synthetic analogues, intentional self-harm
        • T38.0X3 Poisoning by glucocorticoids and synthetic analogues, assault
        • T38.0X4 Poisoning by glucocorticoids and synthetic analogues, undetermined
        • T38.0X5 Adverse effect of glucocorticoids and synthetic analogues
        • T38.0X6 Underdosing of glucocorticoids and synthetic analogues
    2. T38.1 Poisoning by, adverse effect of and underdosing of thyroid hormones and substitutes

      1. T38.1X Poisoning by, adverse effect of and underdosing of thyroid hormones and substitutes

        • T38.1X1 Poisoning by thyroid hormones and substitutes, accidental (unintentional)

          Inclusion term(s):

          • Poisoning by thyroid hormones and substitutes NOS
        • T38.1X2 Poisoning by thyroid hormones and substitutes, intentional self-harm
        • T38.1X3 Poisoning by thyroid hormones and substitutes, assault
        • T38.1X4 Poisoning by thyroid hormones and substitutes, undetermined
        • T38.1X5 Adverse effect of thyroid hormones and substitutes
        • T38.1X6 Underdosing of thyroid hormones and substitutes
    3. T38.2 Poisoning by, adverse effect of and underdosing of antithyroid drugs

      1. T38.2X Poisoning by, adverse effect of and underdosing of antithyroid drugs

        • T38.2X1 Poisoning by antithyroid drugs, accidental (unintentional)

          Inclusion term(s):

          • Poisoning by antithyroid drugs NOS
        • T38.2X2 Poisoning by antithyroid drugs, intentional self-harm
        • T38.2X3 Poisoning by antithyroid drugs, assault
        • T38.2X4 Poisoning by antithyroid drugs, undetermined
        • T38.2X5 Adverse effect of antithyroid drugs
        • T38.2X6 Underdosing of antithyroid drugs
    4. T38.3 Poisoning by, adverse effect of and underdosing of insulin and oral hypoglycemic [antidiabetic] drugs

      1. T38.3X Poisoning by, adverse effect of and underdosing of insulin and oral hypoglycemic [antidiabetic] drugs

        • T38.3X1 Poisoning by insulin and oral hypoglycemic [antidiabetic] drugs, accidental (unintentional)

          Inclusion term(s):

          • Poisoning by insulin and oral hypoglycemic [antidiabetic] drugs NOS
        • T38.3X2 Poisoning by insulin and oral hypoglycemic [antidiabetic] drugs, intentional self-harm
        • T38.3X3 Poisoning by insulin and oral hypoglycemic [antidiabetic] drugs, assault
        • T38.3X4 Poisoning by insulin and oral hypoglycemic [antidiabetic] drugs, undetermined
        • T38.3X5 Adverse effect of insulin and oral hypoglycemic [antidiabetic] drugs
        • T38.3X6 Underdosing of insulin and oral hypoglycemic [antidiabetic] drugs
    5. T38.4 Poisoning by, adverse effect of and underdosing of oral contraceptives

      Inclusion term(s):

      • Poisoning by, adverse effect of and underdosing of multiple- and single-ingredient oral contraceptive preparations
      1. T38.4X Poisoning by, adverse effect of and underdosing of oral contraceptives

        • T38.4X1 Poisoning by oral contraceptives, accidental (unintentional)

          Inclusion term(s):

          • Poisoning by oral contraceptives NOS
        • T38.4X2 Poisoning by oral contraceptives, intentional self-harm
        • T38.4X3 Poisoning by oral contraceptives, assault
        • T38.4X4 Poisoning by oral contraceptives, undetermined
        • T38.4X5 Adverse effect of oral contraceptives
        • T38.4X6 Underdosing of oral contraceptives
    6. T38.5 Poisoning by, adverse effect of and underdosing of other estrogens and progestogens

      Inclusion term(s):

      • Poisoning by, adverse effect of and underdosing of estrogens and progestogens mixtures and substitutes
      1. T38.5X Poisoning by, adverse effect of and underdosing of other estrogens and progestogens

        • T38.5X1 Poisoning by other estrogens and progestogens, accidental (unintentional)

          Inclusion term(s):

          • Poisoning by other estrogens and progestogens NOS
        • T38.5X2 Poisoning by other estrogens and progestogens, intentional self-harm
        • T38.5X3 Poisoning by other estrogens and progestogens, assault
        • T38.5X4 Poisoning by other estrogens and progestogens, undetermined
        • T38.5X5 Adverse effect of other estrogens and progestogens
        • T38.5X6 Underdosing of other estrogens and progestogens
    7. T38.6 Poisoning by, adverse effect of and underdosing of antigonadotrophins, antiestrogens, antiandrogens, not elsewhere classified

      Inclusion term(s):

      • Poisoning by, adverse effect of and underdosing of tamoxifen
      1. T38.6X Poisoning by, adverse effect of and underdosing of antigonadotrophins, antiestrogens, antiandrogens, not elsewhere classified

        • T38.6X1 Poisoning by antigonadotrophins, antiestrogens, antiandrogens, not elsewhere classified, accidental (unintentional)

          Inclusion term(s):

          • Poisoning by antigonadotrophins, antiestrogens, antiandrogens, not elsewhere classified NOS
        • T38.6X2 Poisoning by antigonadotrophins, antiestrogens, antiandrogens, not elsewhere classified, intentional self-harm
        • T38.6X3 Poisoning by antigonadotrophins, antiestrogens, antiandrogens, not elsewhere classified, assault
        • T38.6X4 Poisoning by antigonadotrophins, antiestrogens, antiandrogens, not elsewhere classified, undetermined
        • T38.6X5 Adverse effect of antigonadotrophins, antiestrogens, antiandrogens, not elsewhere classified
        • T38.6X6 Underdosing of antigonadotrophins, antiestrogens, antiandrogens, not elsewhere classified
    8. T38.7 Poisoning by, adverse effect of and underdosing of androgens and anabolic congeners

      1. T38.7X Poisoning by, adverse effect of and underdosing of androgens and anabolic congeners

        • T38.7X1 Poisoning by androgens and anabolic congeners, accidental (unintentional)

          Inclusion term(s):

          • Poisoning by androgens and anabolic congeners NOS
        • T38.7X2 Poisoning by androgens and anabolic congeners, intentional self-harm
        • T38.7X3 Poisoning by androgens and anabolic congeners, assault
        • T38.7X4 Poisoning by androgens and anabolic congeners, undetermined
        • T38.7X5 Adverse effect of androgens and anabolic congeners
        • T38.7X6 Underdosing of androgens and anabolic congeners
    9. T38.8 Poisoning by, adverse effect of and underdosing of other and unspecified hormones and synthetic substitutes

      1. T38.80 Poisoning by, adverse effect of and underdosing of unspecified hormones and synthetic substitutes

        • T38.801 Poisoning by unspecified hormones and synthetic substitutes, accidental (unintentional)

          Inclusion term(s):

          • Poisoning by unspecified hormones and synthetic substitutes NOS
        • T38.802 Poisoning by unspecified hormones and synthetic substitutes, intentional self-harm
        • T38.803 Poisoning by unspecified hormones and synthetic substitutes, assault
        • T38.804 Poisoning by unspecified hormones and synthetic substitutes, undetermined
        • T38.805 Adverse effect of unspecified hormones and synthetic substitutes
        • T38.806 Underdosing of unspecified hormones and synthetic substitutes
      2. T38.81 Poisoning by, adverse effect of and underdosing of anterior pituitary [adenohypophyseal] hormones

        • T38.811 Poisoning by anterior pituitary [adenohypophyseal] hormones, accidental (unintentional)

          Inclusion term(s):

          • Poisoning by anterior pituitary [adenohypophyseal] hormones NOS
        • T38.812 Poisoning by anterior pituitary [adenohypophyseal] hormones, intentional self-harm
        • T38.813 Poisoning by anterior pituitary [adenohypophyseal] hormones, assault
        • T38.814 Poisoning by anterior pituitary [adenohypophyseal] hormones, undetermined
        • T38.815 Adverse effect of anterior pituitary [adenohypophyseal] hormones
        • T38.816 Underdosing of anterior pituitary [adenohypophyseal] hormones
      3. T38.89 Poisoning by, adverse effect of and underdosing of other hormones and synthetic substitutes

        • T38.891 Poisoning by other hormones and synthetic substitutes, accidental (unintentional)

          Inclusion term(s):

          • Poisoning by other hormones and synthetic substitutes NOS
        • T38.892 Poisoning by other hormones and synthetic substitutes, intentional self-harm
        • T38.893 Poisoning by other hormones and synthetic substitutes, assault
        • T38.894 Poisoning by other hormones and synthetic substitutes, undetermined
        • T38.895 Adverse effect of other hormones and synthetic substitutes
        • T38.896 Underdosing of other hormones and synthetic substitutes
    10. T38.9 Poisoning by, adverse effect of and underdosing of other and unspecified hormone antagonists

      1. T38.90 Poisoning by, adverse effect of and underdosing of unspecified hormone antagonists

        • T38.901 Poisoning by unspecified hormone antagonists, accidental (unintentional)

          Inclusion term(s):

          • Poisoning by unspecified hormone antagonists NOS
        • T38.902 Poisoning by unspecified hormone antagonists, intentional self-harm
        • T38.903 Poisoning by unspecified hormone antagonists, assault
        • T38.904 Poisoning by unspecified hormone antagonists, undetermined
        • T38.905 Adverse effect of unspecified hormone antagonists
        • T38.906 Underdosing of unspecified hormone antagonists
      2. T38.99 Poisoning by, adverse effect of and underdosing of other hormone antagonists

        • T38.991 Poisoning by other hormone antagonists, accidental (unintentional)

          Inclusion term(s):

          • Poisoning by other hormone antagonists NOS
        • T38.992 Poisoning by other hormone antagonists, intentional self-harm
        • T38.993 Poisoning by other hormone antagonists, assault
        • T38.994 Poisoning by other hormone antagonists, undetermined
        • T38.995 Adverse effect of other hormone antagonists
        • T38.996 Underdosing of other hormone antagonists
Abbreviations used here:

NEC Not elsewhere classifiable
This abbreviation in the Tabular List represents “other specified”. When a specific code is not available for a condition, the Tabular List includes an NEC entry under a code to identify the code as the “other specified” code.

NOS Not otherwise specified
This abbreviation is the equivalent of unspecified.