The drug giving rise to the adverse effect should be identified by use of codes from categories T36-T50 with fifth or sixth character 5.

Use additional code(s) to specify:
manifestations of poisoning
underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
underdosing of medication regimen (Z91.12-, Z91.13-)

Code first  , for adverse effects, the nature of the adverse effect, such as:
  adverse effect NOS (T88.7)
  aspirin gastritis (K29.-)
  blood disorders (D56-D76)
  contact dermatitis (L23-L25)
  dermatitis due to substances taken internally (L27.-)
  nephropathy (N14.0-N14.2)

Includes:

  • adverse effect of correct substance properly administered
  • poisoning by overdose of substance
  • poisoning by wrong substance given or taken in error
  • underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed

Excludes1

  • toxic reaction to local anesthesia in pregnancy (O29.3-)

Excludes2

  • abuse and dependence of psychoactive substances (F10-F19)
  • abuse of non-dependence-producing substances (F55.-)
  • immunodeficiency due to drugs (D84.821)
  • drug reaction and poisoning affecting newborn (P00-P96)
  • pathological drug intoxication (inebriation) (F10-F19)
  1. T44 Poisoning by, adverse effect of and underdosing of drugs primarily affecting the autonomic nervous system

    The appropriate 7th character is to be added to each code from category T44

    • A - initial encounter
    • D - subsequent encounter
    • S - sequela
    1. T44.0 Poisoning by, adverse effect of and underdosing of anticholinesterase agents

      1. T44.0X Poisoning by, adverse effect of and underdosing of anticholinesterase agents

        • T44.0X1 Poisoning by anticholinesterase agents, accidental (unintentional)

          Inclusion term(s):

          • Poisoning by anticholinesterase agents NOS
        • T44.0X2 Poisoning by anticholinesterase agents, intentional self-harm
        • T44.0X3 Poisoning by anticholinesterase agents, assault
        • T44.0X4 Poisoning by anticholinesterase agents, undetermined
        • T44.0X5 Adverse effect of anticholinesterase agents
        • T44.0X6 Underdosing of anticholinesterase agents
    2. T44.1 Poisoning by, adverse effect of and underdosing of other parasympathomimetics [cholinergics]

      1. T44.1X Poisoning by, adverse effect of and underdosing of other parasympathomimetics [cholinergics]

        • T44.1X1 Poisoning by other parasympathomimetics [cholinergics], accidental (unintentional)

          Inclusion term(s):

          • Poisoning by other parasympathomimetics [cholinergics] NOS
        • T44.1X2 Poisoning by other parasympathomimetics [cholinergics], intentional self-harm
        • T44.1X3 Poisoning by other parasympathomimetics [cholinergics], assault
        • T44.1X4 Poisoning by other parasympathomimetics [cholinergics], undetermined
        • T44.1X5 Adverse effect of other parasympathomimetics [cholinergics]
        • T44.1X6 Underdosing of other parasympathomimetics [cholinergics]
    3. T44.2 Poisoning by, adverse effect of and underdosing of ganglionic blocking drugs

      1. T44.2X Poisoning by, adverse effect of and underdosing of ganglionic blocking drugs

        • T44.2X1 Poisoning by ganglionic blocking drugs, accidental (unintentional)

          Inclusion term(s):

          • Poisoning by ganglionic blocking drugs NOS
        • T44.2X2 Poisoning by ganglionic blocking drugs, intentional self-harm
        • T44.2X3 Poisoning by ganglionic blocking drugs, assault
        • T44.2X4 Poisoning by ganglionic blocking drugs, undetermined
        • T44.2X5 Adverse effect of ganglionic blocking drugs
        • T44.2X6 Underdosing of ganglionic blocking drugs
    4. T44.3 Poisoning by, adverse effect of and underdosing of other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics

      Inclusion term(s):

      • Poisoning by, adverse effect of and underdosing of papaverine
      1. T44.3X Poisoning by, adverse effect of and underdosing of other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics

        • T44.3X1 Poisoning by other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, accidental (unintentional)

          Inclusion term(s):

          • Poisoning by other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics NOS
        • T44.3X2 Poisoning by other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, intentional self-harm
        • T44.3X3 Poisoning by other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, assault
        • T44.3X4 Poisoning by other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, undetermined
        • T44.3X5 Adverse effect of other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics
        • T44.3X6 Underdosing of other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics
    5. T44.4 Poisoning by, adverse effect of and underdosing of predominantly alpha-adrenoreceptor agonists

      Inclusion term(s):

      • Poisoning by, adverse effect of and underdosing of metaraminol
      1. T44.4X Poisoning by, adverse effect of and underdosing of predominantly alpha-adrenoreceptor agonists

        • T44.4X1 Poisoning by predominantly alpha-adrenoreceptor agonists, accidental (unintentional)

          Inclusion term(s):

          • Poisoning by predominantly alpha-adrenoreceptor agonists NOS
        • T44.4X2 Poisoning by predominantly alpha-adrenoreceptor agonists, intentional self-harm
        • T44.4X3 Poisoning by predominantly alpha-adrenoreceptor agonists, assault
        • T44.4X4 Poisoning by predominantly alpha-adrenoreceptor agonists, undetermined
        • T44.4X5 Adverse effect of predominantly alpha-adrenoreceptor agonists
        • T44.4X6 Underdosing of predominantly alpha-adrenoreceptor agonists
    6. T44.5 Poisoning by, adverse effect of and underdosing of predominantly beta-adrenoreceptor agonists

      1. T44.5X Poisoning by, adverse effect of and underdosing of predominantly beta-adrenoreceptor agonists

        • T44.5X1 Poisoning by predominantly beta-adrenoreceptor agonists, accidental (unintentional)

          Inclusion term(s):

          • Poisoning by predominantly beta-adrenoreceptor agonists NOS
        • T44.5X2 Poisoning by predominantly beta-adrenoreceptor agonists, intentional self-harm
        • T44.5X3 Poisoning by predominantly beta-adrenoreceptor agonists, assault
        • T44.5X4 Poisoning by predominantly beta-adrenoreceptor agonists, undetermined
        • T44.5X5 Adverse effect of predominantly beta-adrenoreceptor agonists
        • T44.5X6 Underdosing of predominantly beta-adrenoreceptor agonists
    7. T44.6 Poisoning by, adverse effect of and underdosing of alpha-adrenoreceptor antagonists

      1. T44.6X Poisoning by, adverse effect of and underdosing of alpha-adrenoreceptor antagonists

        • T44.6X1 Poisoning by alpha-adrenoreceptor antagonists, accidental (unintentional)

          Inclusion term(s):

          • Poisoning by alpha-adrenoreceptor antagonists NOS
        • T44.6X2 Poisoning by alpha-adrenoreceptor antagonists, intentional self-harm
        • T44.6X3 Poisoning by alpha-adrenoreceptor antagonists, assault
        • T44.6X4 Poisoning by alpha-adrenoreceptor antagonists, undetermined
        • T44.6X5 Adverse effect of alpha-adrenoreceptor antagonists
        • T44.6X6 Underdosing of alpha-adrenoreceptor antagonists
    8. T44.7 Poisoning by, adverse effect of and underdosing of beta-adrenoreceptor antagonists

      1. T44.7X Poisoning by, adverse effect of and underdosing of beta-adrenoreceptor antagonists

        • T44.7X1 Poisoning by beta-adrenoreceptor antagonists, accidental (unintentional)

          Inclusion term(s):

          • Poisoning by beta-adrenoreceptor antagonists NOS
        • T44.7X2 Poisoning by beta-adrenoreceptor antagonists, intentional self-harm
        • T44.7X3 Poisoning by beta-adrenoreceptor antagonists, assault
        • T44.7X4 Poisoning by beta-adrenoreceptor antagonists, undetermined
        • T44.7X5 Adverse effect of beta-adrenoreceptor antagonists
        • T44.7X6 Underdosing of beta-adrenoreceptor antagonists
    9. T44.8 Poisoning by, adverse effect of and underdosing of centrally-acting and adrenergic-neuron- blocking agents

      1. T44.8X Poisoning by, adverse effect of and underdosing of centrally-acting and adrenergic- neuron-blocking agents

        • T44.8X1 Poisoning by centrally-acting and adrenergic-neuron-blocking agents, accidental (unintentional)

          Inclusion term(s):

          • Poisoning by centrally-acting and adrenergic-neuron-blocking agents NOS
        • T44.8X2 Poisoning by centrally-acting and adrenergic-neuron-blocking agents, intentional self-harm
        • T44.8X3 Poisoning by centrally-acting and adrenergic-neuron-blocking agents, assault
        • T44.8X4 Poisoning by centrally-acting and adrenergic-neuron-blocking agents, undetermined
        • T44.8X5 Adverse effect of centrally-acting and adrenergic-neuron-blocking agents
        • T44.8X6 Underdosing of centrally-acting and adrenergic-neuron-blocking agents
    10. T44.9 Poisoning by, adverse effect of and underdosing of other and unspecified drugs primarily affecting the autonomic nervous system

      Inclusion term(s):

      • Poisoning by, adverse effect of and underdosing of drug stimulating both alpha and beta-adrenoreceptors
      1. T44.90 Poisoning by, adverse effect of and underdosing of unspecified drugs primarily affecting the autonomic nervous system

        • T44.901 Poisoning by unspecified drugs primarily affecting the autonomic nervous system, accidental (unintentional)

          Inclusion term(s):

          • Poisoning by unspecified drugs primarily affecting the autonomic nervous system NOS
        • T44.902 Poisoning by unspecified drugs primarily affecting the autonomic nervous system, intentional self-harm
        • T44.903 Poisoning by unspecified drugs primarily affecting the autonomic nervous system, assault
        • T44.904 Poisoning by unspecified drugs primarily affecting the autonomic nervous system, undetermined
        • T44.905 Adverse effect of unspecified drugs primarily affecting the autonomic nervous system
        • T44.906 Underdosing of unspecified drugs primarily affecting the autonomic nervous system
      2. T44.99 Poisoning by, adverse effect of and underdosing of other drugs primarily affecting the autonomic nervous system

        • T44.991 Poisoning by other drug primarily affecting the autonomic nervous system, accidental (unintentional)

          Inclusion term(s):

          • Poisoning by other drugs primarily affecting the autonomic nervous system NOS
        • T44.992 Poisoning by other drug primarily affecting the autonomic nervous system, intentional self-harm
        • T44.993 Poisoning by other drug primarily affecting the autonomic nervous system, assault
        • T44.994 Poisoning by other drug primarily affecting the autonomic nervous system, undetermined
        • T44.995 Adverse effect of other drug primarily affecting the autonomic nervous system
        • T44.996 Underdosing of other drug primarily affecting the autonomic nervous system
Abbreviations used here:

NEC Not elsewhere classifiable
This abbreviation in the Tabular List represents “other specified”. When a specific code is not available for a condition, the Tabular List includes an NEC entry under a code to identify the code as the “other specified” code.

NOS Not otherwise specified
This abbreviation is the equivalent of unspecified.