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Substance Poisoning
Accidental (unintentional)
Poisoning
Intentional (self-harm)
Poisoning
Assault
Poisoning
Undetermined
Adverse
Effect
Underdosing
Indocyanine green T50.8X1 T50.8X2 T50.8X3 T50.8X4 T50.8X5 T50.8X6
Indometacin T39.391 T39.392 T39.393 T39.394 T39.395 T39.396
Indomethacin T39.391 T39.392 T39.393 T39.394 T39.395 T39.396
– farnesil T39.4X1 T39.4X2 T39.4X3 T39.4X4 T39.4X5 T39.4X6
Indoramin T44.6X1 T44.6X2 T44.6X3 T44.6X4 T44.6X5 T44.6X6
Industrial
– alcohol T51.0X1 T51.0X2 T51.0X3 T51.0X4 -- --
– fumes T59.891 T59.892 T59.893 T59.894 -- --
– solvents (fumes) (vapors) T52.91 T52.92 T52.93 T52.94 -- --
Influenza vaccine T50.B91 T50.B92 T50.B93 T50.B94 T50.B95 T50.B96
Ingested substance NEC T65.91 T65.92 T65.93 T65.94 -- --
INH T37.1X1 T37.1X2 T37.1X3 T37.1X4 T37.1X5 T37.1X6
Inhibitor
– angiotensin-converting enzyme T46.4X1 T46.4X2 T46.4X3 T46.4X4 T46.4X5 T46.4X6
– carbonic anhydrase T50.2X1 T50.2X2 T50.2X3 T50.2X4 T50.2X5 T50.2X6
– fibrinolysis T45.621 T45.622 T45.623 T45.624 T45.625 T45.626
– monoamine oxidase NEC T43.1X1 T43.1X2 T43.1X3 T43.1X4 T43.1X5 T43.1X6
– – hydrazine T43.1X1 T43.1X2 T43.1X3 T43.1X4 T43.1X5 T43.1X6
– postsynaptic T43.8X1 T43.8X2 T43.8X3 T43.8X4 T43.8X5 T43.8X6
– prothrombin synthesis T45.511 T45.512 T45.513 T45.514 T45.515 T45.516
Ink T65.891 T65.892 T65.893 T65.894 -- --

The occurrence of drug toxicity is classified in ICD-10-CM as follows:

Adverse Effect

When coding an adverse effect of a drug that has been correctly prescribed and properly administered, assign the appropriate code for the nature of the adverse effect followed by the appropriate code for the adverse effect of the drug (T36-T50). The code for the drug should have a 5th or 6th character “5” (for example T36.0X5-) Examples of the nature of an adverse effect are tachycardia, delirium, gastrointestinal hemorrhaging, vomiting, hypokalemia, hepatitis, renal failure, or respiratory failure.

Poisoning

When coding a poisoning or reaction to the improper use of a medication (e.g., overdose, wrong substance given or taken in error, wrong route of administration), first assign the appropriate code from categories T36-T50. The poisoning codes have an associated intent as their 5th or 6th character (accidental, intentional self-harm, assault and undetermined. If the intent of the poisoning is unknown or unspecified, code the intent as accidental intent. The undetermined intent is only for use if the documentation in the record specifies that the intent cannot be determined. Use additional code(s) for all manifestations of poisonings.

If there is also a diagnosis of abuse or dependence of the substance, the abuse or dependence is assigned as an additional code.

Examples of poisoning include:
  • Error was made in drug prescription
    Errors made in drug prescription or in the administration of the drug by provider, nurse, patient, or other person.
  • Overdose of a drug intentionally taken
    If an overdose of a drug was intentionally taken or administered and resulted in drug toxicity, it would be coded as a poisoning.
  • Nonprescribed drug taken with correctly prescribed and properly administered drug
    If a nonprescribed drug or medicinal agent was taken in combination with a correctly prescribed and properly administered drug, any drug toxicity or other reaction resulting from the interaction of the two drugs would be classified as a poisoning.
  • Interaction of drug(s) and alcohol
    When a reaction results from the interaction of a drug(s) and alcohol, this would be classified as poisoning.
Underdosing

Underdosing refers to taking less of a medication than is prescribed by a provider or a manufacturer's instruction. Discontinuing the use of a prescribed medication on the patient's own initiative (not directed by the patient's provider) is also classified as an underdosing. For underdosing, assign the code from categories T36-T50 (fifth or sixth character “6”).

Codes for underdosing should never be assigned as principal or first-listed codes. If a patient has a relapse or exacerbation of the medical condition for which the drug is prescribed because of the reduction in dose, then the medical condition itself should be coded.

Noncompliance (Z91.12-, Z91.13- and Z91.14-) or complication of care (Y63.6-Y63.9) codes are to be used with an underdosing code to indicate intent, if known.

Toxic Effects

When a harmful substance is ingested or comes in contact with a person, this is classified as a toxic effect. The toxic effect codes are in categories T51-T65.

Toxic effect codes have an associated intent: accidental, intentional self-harm, assault and undetermined.