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Substance Poisoning
Accidental (unintentional)
Poisoning
Intentional (self-harm)
Poisoning
Assault
Poisoning
Undetermined
Adverse
Effect
Underdosing
Methoxypromazine T43.3X1 T43.3X2 T43.3X3 T43.3X4 T43.3X5 T43.3X6
5-Methoxypsoralen (5-MOP) T50.991 T50.992 T50.993 T50.994 T50.995 T50.996
8-Methoxypsoralen (8-MOP) T50.991 T50.992 T50.993 T50.994 T50.995 T50.996
Methscopolamine bromide T44.3X1 T44.3X2 T44.3X3 T44.3X4 T44.3X5 T44.3X6
Methsuximide T42.2X1 T42.2X2 T42.2X3 T42.2X4 T42.2X5 T42.2X6
Methyclothiazide T50.2X1 T50.2X2 T50.2X3 T50.2X4 T50.2X5 T50.2X6
Methyl
– acetate T52.4X1 T52.4X2 T52.4X3 T52.4X4 -- --
– acetone T52.4X1 T52.4X2 T52.4X3 T52.4X4 -- --
– acrylate T65.891 T65.892 T65.893 T65.894 -- --
– alcohol T51.1X1 T51.1X2 T51.1X3 T51.1X4 -- --
– aminophenol T65.3X1 T65.3X2 T65.3X3 T65.3X4 -- --
– amphetamine T43.651 T43.652 T43.653 T43.654 T43.655 T43.656
– androstanolone T38.7X1 T38.7X2 T38.7X3 T38.7X4 T38.7X5 T38.7X6
– atropine T44.3X1 T44.3X2 T44.3X3 T44.3X4 T44.3X5 T44.3X6
– benzene T52.2X1 T52.2X2 T52.2X3 T52.2X4 -- --
– benzoate T52.8X1 T52.8X2 T52.8X3 T52.8X4 -- --
– benzol T52.2X1 T52.2X2 T52.2X3 T52.2X4 -- --
– bromide (gas) T59.891 T59.892 T59.893 T59.894 -- --
– – fumigant T60.8X1 T60.8X2 T60.8X3 T60.8X4 -- --
– butanol T51.3X1 T51.3X2 T51.3X3 T51.3X4 -- --
– carbinol T51.1X1 T51.1X2 T51.1X3 T51.1X4 -- --
– carbonate T52.8X1 T52.8X2 T52.8X3 T52.8X4 -- --
– CCNU T45.1X1 T45.1X2 T45.1X3 T45.1X4 T45.1X5 T45.1X6
– cellosolve T52.91 T52.92 T52.93 T52.94 -- --
– cellulose T47.4X1 T47.4X2 T47.4X3 T47.4X4 T47.4X5 T47.4X6
– chloride (gas) T59.891 T59.892 T59.893 T59.894 -- --
– chloroformate T59.3X1 T59.3X2 T59.3X3 T59.3X4 -- --
– cyclohexane T52.8X1 T52.8X2 T52.8X3 T52.8X4 -- --
– cyclohexanol T51.8X1 T51.8X2 T51.8X3 T51.8X4 -- --
– cyclohexanone T52.8X1 T52.8X2 T52.8X3 T52.8X4 -- --
– cyclohexyl acetate T52.8X1 T52.8X2 T52.8X3 T52.8X4 -- --
– demeton T60.0X1 T60.0X2 T60.0X3 T60.0X4 -- --
– dihydromorphinone T40.2X1 T40.2X2 T40.2X3 T40.2X4 T40.2X5 T40.2X6
– ergometrine T48.0X1 T48.0X2 T48.0X3 T48.0X4 T48.0X5 T48.0X6
– ergonovine T48.0X1 T48.0X2 T48.0X3 T48.0X4 T48.0X5 T48.0X6
– ethyl ketone T52.4X1 T52.4X2 T52.4X3 T52.4X4 -- --
– glucamine antimonate T37.8X1 T37.8X2 T37.8X3 T37.8X4 T37.8X5 T37.8X6
– hydrazine T65.891 T65.892 T65.893 T65.894 -- --
– iodide T65.891 T65.892 T65.893 T65.894 -- --
– isobutyl ketone T52.4X1 T52.4X2 T52.4X3 T52.4X4 -- --
– isothiocyanate T60.3X1 T60.3X2 T60.3X3 T60.3X4 -- --
– mercaptan T59.891 T59.892 T59.893 T59.894 -- --
– morphine NEC T40.2X1 T40.2X2 T40.2X3 T40.2X4 T40.2X5 T40.2X6
– nicotinate T49.4X1 T49.4X2 T49.4X3 T49.4X4 T49.4X5 T49.4X6
– paraben T49.0X1 T49.0X2 T49.0X3 T49.0X4 T49.0X5 T49.0X6
– parafynol T42.6X1 T42.6X2 T42.6X3 T42.6X4 T42.6X5 T42.6X6
– parathion T60.0X1 T60.0X2 T60.0X3 T60.0X4 -- --
– peridol T43.4X1 T43.4X2 T43.4X3 T43.4X4 T43.4X5 T43.4X6
– phenidate T43.631 T43.632 T43.633 T43.634 T43.635 T43.636
– prednisolone T38.0X1 T38.0X2 T38.0X3 T38.0X4 T38.0X5 T38.0X6
– – ENT agent T49.6X1 T49.6X2 T49.6X3 T49.6X4 T49.6X5 T49.6X6
– – ophthalmic preparation T49.5X1 T49.5X2 T49.5X3 T49.5X4 T49.5X5 T49.5X6
– – topical NEC T49.0X1 T49.0X2 T49.0X3 T49.0X4 T49.0X5 T49.0X6
– propylcarbinol T51.3X1 T51.3X2 T51.3X3 T51.3X4 -- --
– rosaniline NEC T49.0X1 T49.0X2 T49.0X3 T49.0X4 T49.0X5 T49.0X6
– salicylate T49.2X1 T49.2X2 T49.2X3 T49.2X4 T49.2X5 T49.2X6
– sulfate (fumes) T59.891 T59.892 T59.893 T59.894 -- --
– – liquid T52.8X1 T52.8X2 T52.8X3 T52.8X4 -- --
– sulfonal T42.6X1 T42.6X2 T42.6X3 T42.6X4 T42.6X5 T42.6X6
– testosterone T38.7X1 T38.7X2 T38.7X3 T38.7X4 T38.7X5 T38.7X6
– thiouracil T38.2X1 T38.2X2 T38.2X3 T38.2X4 T38.2X5 T38.2X6
Methylamphetamine T43.651 T43.652 T43.653 T43.654 T43.655 T43.656
Methylated spirit T51.1X1 T51.1X2 T51.1X3 T51.1X4 -- --
Methylatropine nitrate T44.3X1 T44.3X2 T44.3X3 T44.3X4 T44.3X5 T44.3X6

The occurrence of drug toxicity is classified in ICD-10-CM as follows:

Adverse Effect

When coding an adverse effect of a drug that has been correctly prescribed and properly administered, assign the appropriate code for the nature of the adverse effect followed by the appropriate code for the adverse effect of the drug (T36-T50). The code for the drug should have a 5th or 6th character “5” (for example T36.0X5-) Examples of the nature of an adverse effect are tachycardia, delirium, gastrointestinal hemorrhaging, vomiting, hypokalemia, hepatitis, renal failure, or respiratory failure.

Poisoning

When coding a poisoning or reaction to the improper use of a medication (e.g., overdose, wrong substance given or taken in error, wrong route of administration), first assign the appropriate code from categories T36-T50. The poisoning codes have an associated intent as their 5th or 6th character (accidental, intentional self-harm, assault and undetermined. If the intent of the poisoning is unknown or unspecified, code the intent as accidental intent. The undetermined intent is only for use if the documentation in the record specifies that the intent cannot be determined. Use additional code(s) for all manifestations of poisonings.

If there is also a diagnosis of abuse or dependence of the substance, the abuse or dependence is assigned as an additional code.

Examples of poisoning include:
  • Error was made in drug prescription
    Errors made in drug prescription or in the administration of the drug by provider, nurse, patient, or other person.
  • Overdose of a drug intentionally taken
    If an overdose of a drug was intentionally taken or administered and resulted in drug toxicity, it would be coded as a poisoning.
  • Nonprescribed drug taken with correctly prescribed and properly administered drug
    If a nonprescribed drug or medicinal agent was taken in combination with a correctly prescribed and properly administered drug, any drug toxicity or other reaction resulting from the interaction of the two drugs would be classified as a poisoning.
  • Interaction of drug(s) and alcohol
    When a reaction results from the interaction of a drug(s) and alcohol, this would be classified as poisoning.
Underdosing

Underdosing refers to taking less of a medication than is prescribed by a provider or a manufacturer's instruction. Discontinuing the use of a prescribed medication on the patient's own initiative (not directed by the patient's provider) is also classified as an underdosing. For underdosing, assign the code from categories T36-T50 (fifth or sixth character “6”).

Codes for underdosing should never be assigned as principal or first-listed codes. If a patient has a relapse or exacerbation of the medical condition for which the drug is prescribed because of the reduction in dose, then the medical condition itself should be coded.

Noncompliance (Z91.12-, Z91.13- and Z91.14-) or complication of care (Y63.6-Y63.9) codes are to be used with an underdosing code to indicate intent, if known.

Toxic Effects

When a harmful substance is ingested or comes in contact with a person, this is classified as a toxic effect. The toxic effect codes are in categories T51-T65.

Toxic effect codes have an associated intent: accidental, intentional self-harm, assault and undetermined.