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Substance Poisoning
Accidental (unintentional)
Poisoning
Intentional (self-harm)
Poisoning
Assault
Poisoning
Undetermined
Adverse
Effect
Underdosing
Psychostimulant T43.601 T43.602 T43.603 T43.604 T43.605 T43.606
– amphetamine T43.621 T43.622 T43.623 T43.624 T43.625 T43.626
– caffeine T43.611 T43.612 T43.613 T43.614 T43.615 T43.616
– methylphenidate T43.631 T43.632 T43.633 T43.634 T43.635 T43.636
– specified NEC T43.691 T43.692 T43.693 T43.694 T43.695 T43.696
Psychotherapeutic drug NEC T43.91 T43.92 T43.93 T43.94 T43.95 T43.96
– antidepressants   see also Antidepressant T43.201 T43.202 T43.203 T43.204 T43.205 T43.206
– specified NEC T43.8X1 T43.8X2 T43.8X3 T43.8X4 T43.8X5 T43.8X6
– tranquilizers NEC T43.501 T43.502 T43.503 T43.504 T43.505 T43.506
Psychotomimetic agents T40.901 T40.902 T40.903 T40.904 T40.905 T40.906
Psychotropic drug NEC T43.91 T43.92 T43.93 T43.94 T43.95 T43.96
– specified NEC T43.8X1 T43.8X2 T43.8X3 T43.8X4 T43.8X5 T43.8X6
Psyllium hydrophilic mucilloid T47.4X1 T47.4X2 T47.4X3 T47.4X4 T47.4X5 T47.4X6
Pteroylglutamic acid T45.8X1 T45.8X2 T45.8X3 T45.8X4 T45.8X5 T45.8X6
Pteroyltriglutamate T45.1X1 T45.1X2 T45.1X3 T45.1X4 T45.1X5 T45.1X6
Pulp
– devitalizing paste T49.7X1 T49.7X2 T49.7X3 T49.7X4 T49.7X5 T49.7X6
– dressing T49.7X1 T49.7X2 T49.7X3 T49.7X4 T49.7X5 T49.7X6
Pulsatilla T62.2X1 T62.2X2 T62.2X3 T62.2X4 -- --
Pumpkin seed extract T37.4X1 T37.4X2 T37.4X3 T37.4X4 T37.4X5 T37.4X6

The occurrence of drug toxicity is classified in ICD-10-CM as follows:

Adverse Effect

When coding an adverse effect of a drug that has been correctly prescribed and properly administered, assign the appropriate code for the nature of the adverse effect followed by the appropriate code for the adverse effect of the drug (T36-T50). The code for the drug should have a 5th or 6th character “5” (for example T36.0X5-) Examples of the nature of an adverse effect are tachycardia, delirium, gastrointestinal hemorrhaging, vomiting, hypokalemia, hepatitis, renal failure, or respiratory failure.

Poisoning

When coding a poisoning or reaction to the improper use of a medication (e.g., overdose, wrong substance given or taken in error, wrong route of administration), first assign the appropriate code from categories T36-T50. The poisoning codes have an associated intent as their 5th or 6th character (accidental, intentional self-harm, assault and undetermined. If the intent of the poisoning is unknown or unspecified, code the intent as accidental intent. The undetermined intent is only for use if the documentation in the record specifies that the intent cannot be determined. Use additional code(s) for all manifestations of poisonings.

If there is also a diagnosis of abuse or dependence of the substance, the abuse or dependence is assigned as an additional code.

Examples of poisoning include:
  • Error was made in drug prescription
    Errors made in drug prescription or in the administration of the drug by provider, nurse, patient, or other person.
  • Overdose of a drug intentionally taken
    If an overdose of a drug was intentionally taken or administered and resulted in drug toxicity, it would be coded as a poisoning.
  • Nonprescribed drug taken with correctly prescribed and properly administered drug
    If a nonprescribed drug or medicinal agent was taken in combination with a correctly prescribed and properly administered drug, any drug toxicity or other reaction resulting from the interaction of the two drugs would be classified as a poisoning.
  • Interaction of drug(s) and alcohol
    When a reaction results from the interaction of a drug(s) and alcohol, this would be classified as poisoning.
Underdosing

Underdosing refers to taking less of a medication than is prescribed by a provider or a manufacturer's instruction. Discontinuing the use of a prescribed medication on the patient's own initiative (not directed by the patient's provider) is also classified as an underdosing. For underdosing, assign the code from categories T36-T50 (fifth or sixth character “6”).

Codes for underdosing should never be assigned as principal or first-listed codes. If a patient has a relapse or exacerbation of the medical condition for which the drug is prescribed because of the reduction in dose, then the medical condition itself should be coded.

Noncompliance (Z91.12-, Z91.13- and Z91.14-) or complication of care (Y63.6-Y63.9) codes are to be used with an underdosing code to indicate intent, if known.

Toxic Effects

When a harmful substance is ingested or comes in contact with a person, this is classified as a toxic effect. The toxic effect codes are in categories T51-T65.

Toxic effect codes have an associated intent: accidental, intentional self-harm, assault and undetermined.