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Substance Poisoning
Accidental (unintentional)
Poisoning
Intentional (self-harm)
Poisoning
Assault
Poisoning
Undetermined
Adverse
Effect
Underdosing
Urinary anti-infective T37.8X1 T37.8X2 T37.8X3 T37.8X4 T37.8X5 T37.8X6
Urofollitropin T38.811 T38.812 T38.813 T38.814 T38.815 T38.816
Urokinase T45.611 T45.612 T45.613 T45.614 T45.615 T45.616
Urokon T50.8X1 T50.8X2 T50.8X3 T50.8X4 T50.8X5 T50.8X6
Ursodeoxycholic acid T50.991 T50.992 T50.993 T50.994 T50.995 T50.996
Ursodiol T50.991 T50.992 T50.993 T50.994 T50.995 T50.996
Urtica T62.2X1 T62.2X2 T62.2X3 T62.2X4 -- --
Vaccine NEC T50.Z91 T50.Z92 T50.Z93 T50.Z94 T50.Z95 T50.Z96
– antineoplastic T50.Z91 T50.Z92 T50.Z93 T50.Z94 T50.Z95 T50.Z96
– bacterial NEC T50.A91 T50.A92 T50.A93 T50.A94 T50.A95 T50.A96
– – – other bacterial component T50.A21 T50.A22 T50.A23 T50.A24 T50.A25 T50.A26
– – – pertussis component T50.A11 T50.A12 T50.A13 T50.A14 T50.A15 T50.A16
– – – viral-rickettsial component T50.A21 T50.A22 T50.A23 T50.A24 T50.A25 T50.A26
– – mixed NEC T50.A21 T50.A22 T50.A23 T50.A24 T50.A25 T50.A26
– BCG T50.A91 T50.A92 T50.A93 T50.A94 T50.A95 T50.A96
– cholera T50.A91 T50.A92 T50.A93 T50.A94 T50.A95 T50.A96
– diphtheria T50.A91 T50.A92 T50.A93 T50.A94 T50.A95 T50.A96
– – with tetanus T50.A21 T50.A22 T50.A23 T50.A24 T50.A25 T50.A26
– – – and pertussis T50.A11 T50.A12 T50.A13 T50.A14 T50.A15 T50.A16
– influenza T50.B91 T50.B92 T50.B93 T50.B94 T50.B95 T50.B96
– measles T50.B91 T50.B92 T50.B93 T50.B94 T50.B95 T50.B96
– – with mumps and rubella T50.B91 T50.B92 T50.B93 T50.B94 T50.B95 T50.B96
– meningococcal T50.A91 T50.A92 T50.A93 T50.A94 T50.A95 T50.A96
– mumps T50.B91 T50.B92 T50.B93 T50.B94 T50.B95 T50.B96
– paratyphoid T50.A91 T50.A92 T50.A93 T50.A94 T50.A95 T50.A96
– pertussis T50.A11 T50.A12 T50.A13 T50.A14 T50.A15 T50.A16
– – with diphtheria T50.A11 T50.A12 T50.A13 T50.A14 T50.A15 T50.A16
– – – and tetanus T50.A11 T50.A12 T50.A13 T50.A14 T50.A15 T50.A16
– – with other component T50.A11 T50.A12 T50.A13 T50.A14 T50.A15 T50.A16
– plague T50.A91 T50.A92 T50.A93 T50.A94 T50.A95 T50.A96
– poliomyelitis T50.B91 T50.B92 T50.B93 T50.B94 T50.B95 T50.B96
– poliovirus T50.B91 T50.B92 T50.B93 T50.B94 T50.B95 T50.B96
– rabies T50.B91 T50.B92 T50.B93 T50.B94 T50.B95 T50.B96
– respiratory syncytial virus T50.B91 T50.B92 T50.B93 T50.B94 T50.B95 T50.B96
– rickettsial NEC T50.A91 T50.A92 T50.A93 T50.A94 T50.A95 T50.A96
– – – bacterial component T50.A21 T50.A22 T50.A23 T50.A24 T50.A25 T50.A26
– Rocky Mountain spotted fever T50.A91 T50.A92 T50.A93 T50.A94 T50.A95 T50.A96
– rubella T50.B91 T50.B92 T50.B93 T50.B94 T50.B95 T50.B96
– sabin oral T50.B91 T50.B92 T50.B93 T50.B94 T50.B95 T50.B96
– smallpox T50.B11 T50.B12 T50.B13 T50.B14 T50.B15 T50.B16
– TAB T50.A91 T50.A92 T50.A93 T50.A94 T50.A95 T50.A96
– tetanus T50.A91 T50.A92 T50.A93 T50.A94 T50.A95 T50.A96
– typhoid T50.A91 T50.A92 T50.A93 T50.A94 T50.A95 T50.A96
– typhus T50.A91 T50.A92 T50.A93 T50.A94 T50.A95 T50.A96
– viral NEC T50.B91 T50.B92 T50.B93 T50.B94 T50.B95 T50.B96
– yellow fever T50.B91 T50.B92 T50.B93 T50.B94 T50.B95 T50.B96
Vaccinia immune globulin T50.Z11 T50.Z12 T50.Z13 T50.Z14 T50.Z15 T50.Z16
Vaginal contraceptives T49.8X1 T49.8X2 T49.8X3 T49.8X4 T49.8X5 T49.8X6

The occurrence of drug toxicity is classified in ICD-10-CM as follows:

Adverse Effect

When coding an adverse effect of a drug that has been correctly prescribed and properly administered, assign the appropriate code for the nature of the adverse effect followed by the appropriate code for the adverse effect of the drug (T36-T50). The code for the drug should have a 5th or 6th character “5” (for example T36.0X5-) Examples of the nature of an adverse effect are tachycardia, delirium, gastrointestinal hemorrhaging, vomiting, hypokalemia, hepatitis, renal failure, or respiratory failure.

Poisoning

When coding a poisoning or reaction to the improper use of a medication (e.g., overdose, wrong substance given or taken in error, wrong route of administration), first assign the appropriate code from categories T36-T50. The poisoning codes have an associated intent as their 5th or 6th character (accidental, intentional self-harm, assault and undetermined. If the intent of the poisoning is unknown or unspecified, code the intent as accidental intent. The undetermined intent is only for use if the documentation in the record specifies that the intent cannot be determined. Use additional code(s) for all manifestations of poisonings.

If there is also a diagnosis of abuse or dependence of the substance, the abuse or dependence is assigned as an additional code.

Examples of poisoning include:
  • Error was made in drug prescription
    Errors made in drug prescription or in the administration of the drug by provider, nurse, patient, or other person.
  • Overdose of a drug intentionally taken
    If an overdose of a drug was intentionally taken or administered and resulted in drug toxicity, it would be coded as a poisoning.
  • Nonprescribed drug taken with correctly prescribed and properly administered drug
    If a nonprescribed drug or medicinal agent was taken in combination with a correctly prescribed and properly administered drug, any drug toxicity or other reaction resulting from the interaction of the two drugs would be classified as a poisoning.
  • Interaction of drug(s) and alcohol
    When a reaction results from the interaction of a drug(s) and alcohol, this would be classified as poisoning.
Underdosing

Underdosing refers to taking less of a medication than is prescribed by a provider or a manufacturer's instruction. Discontinuing the use of a prescribed medication on the patient's own initiative (not directed by the patient's provider) is also classified as an underdosing. For underdosing, assign the code from categories T36-T50 (fifth or sixth character “6”).

Codes for underdosing should never be assigned as principal or first-listed codes. If a patient has a relapse or exacerbation of the medical condition for which the drug is prescribed because of the reduction in dose, then the medical condition itself should be coded.

Noncompliance (Z91.12-, Z91.13- and Z91.14-) or complication of care (Y63.6-Y63.9) codes are to be used with an underdosing code to indicate intent, if known.

Toxic Effects

When a harmful substance is ingested or comes in contact with a person, this is classified as a toxic effect. The toxic effect codes are in categories T51-T65.

Toxic effect codes have an associated intent: accidental, intentional self-harm, assault and undetermined.