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Substance Poisoning
Accidental (unintentional)
Poisoning
Intentional (self-harm)
Poisoning
Assault
Poisoning
Undetermined
Adverse
Effect
Underdosing
Caffeine T43.611 T43.612 T43.613 T43.614 T43.615 T43.616
Calabar bean T62.2X1 T62.2X2 T62.2X3 T62.2X4 -- --
Caladium seguinum T62.2X1 T62.2X2 T62.2X3 T62.2X4 -- --
Calamine (lotion) T49.3X1 T49.3X2 T49.3X3 T49.3X4 T49.3X5 T49.3X6
Calcifediol T45.2X1 T45.2X2 T45.2X3 T45.2X4 T45.2X5 T45.2X6
Calciferol T45.2X1 T45.2X2 T45.2X3 T45.2X4 T45.2X5 T45.2X6
Calcitonin T50.991 T50.992 T50.993 T50.994 T50.995 T50.996
Calcitriol T45.2X1 T45.2X2 T45.2X3 T45.2X4 T45.2X5 T45.2X6
Calcium T50.3X1 T50.3X2 T50.3X3 T50.3X4 T50.3X5 T50.3X6
– actylsalicylate T39.011 T39.012 T39.013 T39.014 T39.015 T39.016
– benzamidosalicylate T37.1X1 T37.1X2 T37.1X3 T37.1X4 T37.1X5 T37.1X6
– bromide T42.6X1 T42.6X2 T42.6X3 T42.6X4 T42.6X5 T42.6X6
– bromolactobionate T42.6X1 T42.6X2 T42.6X3 T42.6X4 T42.6X5 T42.6X6
– carbaspirin T39.011 T39.012 T39.013 T39.014 T39.015 T39.016
– carbimide T50.6X1 T50.6X2 T50.6X3 T50.6X4 T50.6X5 T50.6X6
– carbonate T47.1X1 T47.1X2 T47.1X3 T47.1X4 T47.1X5 T47.1X6
– chloride T50.991 T50.992 T50.993 T50.994 T50.995 T50.996
– – anhydrous T50.991 T50.992 T50.993 T50.994 T50.995 T50.996
– cyanide T57.8X1 T57.8X2 T57.8X3 T57.8X4 -- --
– dioctyl sulfosuccinate T47.4X1 T47.4X2 T47.4X3 T47.4X4 T47.4X5 T47.4X6
– disodium edathamil T45.8X1 T45.8X2 T45.8X3 T45.8X4 T45.8X5 T45.8X6
– disodium edetate T45.8X1 T45.8X2 T45.8X3 T45.8X4 T45.8X5 T45.8X6
– dobesilate T46.991 T46.992 T46.993 T46.994 T46.995 T46.996
– EDTA T45.8X1 T45.8X2 T45.8X3 T45.8X4 T45.8X5 T45.8X6
– ferrous citrate T45.4X1 T45.4X2 T45.4X3 T45.4X4 T45.4X5 T45.4X6
– folinate T45.8X1 T45.8X2 T45.8X3 T45.8X4 T45.8X5 T45.8X6
– glubionate T50.3X1 T50.3X2 T50.3X3 T50.3X4 T50.3X5 T50.3X6
– gluconate T50.3X1 T50.3X2 T50.3X3 T50.3X4 T50.3X5 T50.3X6
– gluconogalactogluc-onate T50.3X1 T50.3X2 T50.3X3 T50.3X4 T50.3X5 T50.3X6
– hydrate, hydroxide T54.3X1 T54.3X2 T54.3X3 T54.3X4 -- --
– hypochlorite T54.3X1 T54.3X2 T54.3X3 T54.3X4 -- --
– iodide T48.4X1 T48.4X2 T48.4X3 T48.4X4 T48.4X5 T48.4X6
– ipodate T50.8X1 T50.8X2 T50.8X3 T50.8X4 T50.8X5 T50.8X6
– lactate T50.3X1 T50.3X2 T50.3X3 T50.3X4 T50.3X5 T50.3X6
– leucovorin T45.8X1 T45.8X2 T45.8X3 T45.8X4 T45.8X5 T45.8X6
– mandelate T37.91 T37.92 T37.93 T37.94 T37.95 T37.96
– oxide T54.3X1 T54.3X2 T54.3X3 T54.3X4 -- --
– pantothenate T45.2X1 T45.2X2 T45.2X3 T45.2X4 T45.2X5 T45.2X6
– phosphate T50.3X1 T50.3X2 T50.3X3 T50.3X4 T50.3X5 T50.3X6
– salicylate T39.091 T39.092 T39.093 T39.094 T39.095 T39.096
– salts T50.3X1 T50.3X2 T50.3X3 T50.3X4 T50.3X5 T50.3X6
Calculus-dissolving drug T50.991 T50.992 T50.993 T50.994 T50.995 T50.996

The occurrence of drug toxicity is classified in ICD-10-CM as follows:

Adverse Effect

When coding an adverse effect of a drug that has been correctly prescribed and properly administered, assign the appropriate code for the nature of the adverse effect followed by the appropriate code for the adverse effect of the drug (T36-T50). The code for the drug should have a 5th or 6th character “5” (for example T36.0X5-) Examples of the nature of an adverse effect are tachycardia, delirium, gastrointestinal hemorrhaging, vomiting, hypokalemia, hepatitis, renal failure, or respiratory failure.

Poisoning

When coding a poisoning or reaction to the improper use of a medication (e.g., overdose, wrong substance given or taken in error, wrong route of administration), first assign the appropriate code from categories T36-T50. The poisoning codes have an associated intent as their 5th or 6th character (accidental, intentional self-harm, assault and undetermined. If the intent of the poisoning is unknown or unspecified, code the intent as accidental intent. The undetermined intent is only for use if the documentation in the record specifies that the intent cannot be determined. Use additional code(s) for all manifestations of poisonings.

If there is also a diagnosis of abuse or dependence of the substance, the abuse or dependence is assigned as an additional code.

Examples of poisoning include:
  • Error was made in drug prescription
    Errors made in drug prescription or in the administration of the drug by provider, nurse, patient, or other person.
  • Overdose of a drug intentionally taken
    If an overdose of a drug was intentionally taken or administered and resulted in drug toxicity, it would be coded as a poisoning.
  • Nonprescribed drug taken with correctly prescribed and properly administered drug
    If a nonprescribed drug or medicinal agent was taken in combination with a correctly prescribed and properly administered drug, any drug toxicity or other reaction resulting from the interaction of the two drugs would be classified as a poisoning.
  • Interaction of drug(s) and alcohol
    When a reaction results from the interaction of a drug(s) and alcohol, this would be classified as poisoning.
Underdosing

Underdosing refers to taking less of a medication than is prescribed by a provider or a manufacturer's instruction. Discontinuing the use of a prescribed medication on the patient's own initiative (not directed by the patient's provider) is also classified as an underdosing. For underdosing, assign the code from categories T36-T50 (fifth or sixth character “6”).

Codes for underdosing should never be assigned as principal or first-listed codes. If a patient has a relapse or exacerbation of the medical condition for which the drug is prescribed because of the reduction in dose, then the medical condition itself should be coded.

Noncompliance (Z91.12-, Z91.13- and Z91.14-) or complication of care (Y63.6-Y63.9) codes are to be used with an underdosing code to indicate intent, if known.

Toxic Effects

When a harmful substance is ingested or comes in contact with a person, this is classified as a toxic effect. The toxic effect codes are in categories T51-T65.

Toxic effect codes have an associated intent: accidental, intentional self-harm, assault and undetermined.