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Substance Poisoning
Accidental (unintentional)
Poisoning
Intentional (self-harm)
Poisoning
Assault
Poisoning
Undetermined
Adverse
Effect
Underdosing
Cellulose
– cathartic T47.4X1 T47.4X2 T47.4X3 T47.4X4 T47.4X5 T47.4X6
– hydroxyethyl T47.4X1 T47.4X2 T47.4X3 T47.4X4 T47.4X5 T47.4X6
– nitrates (topical) T49.3X1 T49.3X2 T49.3X3 T49.3X4 T49.3X5 T49.3X6
– oxidized T49.4X1 T49.4X2 T49.4X3 T49.4X4 T49.4X5 T49.4X6
Centipede (bite) T63.411 T63.412 T63.413 T63.414 -- --
Central nervous system
– depressants T42.71 T42.72 T42.73 T42.74 T42.75 T42.76
– – anesthetic (general) T41.201 T41.202 T41.203 T41.204 T41.205 T41.206
– – – gases NEC T41.0X1 T41.0X2 T41.0X3 T41.0X4 T41.0X5 T41.0X6
– – – intravenous T41.1X1 T41.1X2 T41.1X3 T41.1X4 T41.1X5 T41.1X6
– – barbiturates T42.3X1 T42.3X2 T42.3X3 T42.3X4 T42.3X5 T42.3X6
– – benzodiazepines T42.4X1 T42.4X2 T42.4X3 T42.4X4 T42.4X5 T42.4X6
– – bromides T42.6X1 T42.6X2 T42.6X3 T42.6X4 T42.6X5 T42.6X6
– – cannabis sativa T40.711 T40.712 T40.713 T40.714 T40.715 T40.716
– – chloral hydrate T42.6X1 T42.6X2 T42.6X3 T42.6X4 T42.6X5 T42.6X6
– – ethanol T51.0X1 T51.0X2 T51.0X3 T51.0X4 -- --
– – hallucinogenics T40.901 T40.902 T40.903 T40.904 T40.905 T40.906
– – hypnotics T42.71 T42.72 T42.73 T42.74 T42.75 T42.76
– – – specified NEC T42.6X1 T42.6X2 T42.6X3 T42.6X4 T42.6X5 T42.6X6
– – muscle relaxants T42.8X1 T42.8X2 T42.8X3 T42.8X4 T42.8X5 T42.8X6
– – paraldehyde T42.6X1 T42.6X2 T42.6X3 T42.6X4 T42.6X5 T42.6X6
– – sedatives; sedative-hypnotics T42.71 T42.72 T42.73 T42.74 T42.75 T42.76
– – – mixed NEC T42.6X1 T42.6X2 T42.6X3 T42.6X4 T42.6X5 T42.6X6
– – – specified NEC T42.6X1 T42.6X2 T42.6X3 T42.6X4 T42.6X5 T42.6X6
– muscle-tone depressants T42.8X1 T42.8X2 T42.8X3 T42.8X4 T42.8X5 T42.8X6
– stimulants T43.601 T43.602 T43.603 T43.604 T43.605 T43.606
– – amphetamines T43.621 T43.622 T43.623 T43.624 T43.625 T43.626
– – analeptics T50.7X1 T50.7X2 T50.7X3 T50.7X4 T50.7X5 T50.7X6
– – antidepressants T43.201 T43.202 T43.203 T43.204 T43.205 T43.206
– – opiate antagonists T50.7X1 T50.7X2 T50.7X3 T50.7X4 T50.7X5 T50.7X6
– – specified NEC T43.691 T43.692 T43.693 T43.694 T43.695 T43.696
Cephalexin T36.1X1 T36.1X2 T36.1X3 T36.1X4 T36.1X5 T36.1X6
Cephaloglycin T36.1X1 T36.1X2 T36.1X3 T36.1X4 T36.1X5 T36.1X6
Cephaloridine T36.1X1 T36.1X2 T36.1X3 T36.1X4 T36.1X5 T36.1X6
Cephalosporins T36.1X1 T36.1X2 T36.1X3 T36.1X4 T36.1X5 T36.1X6
– N (adicillin) T36.0X1 T36.0X2 T36.0X3 T36.0X4 T36.0X5 T36.0X6
Cephalothin T36.1X1 T36.1X2 T36.1X3 T36.1X4 T36.1X5 T36.1X6
Cephalotin T36.1X1 T36.1X2 T36.1X3 T36.1X4 T36.1X5 T36.1X6
Cephradine T36.1X1 T36.1X2 T36.1X3 T36.1X4 T36.1X5 T36.1X6

The occurrence of drug toxicity is classified in ICD-10-CM as follows:

Adverse Effect

When coding an adverse effect of a drug that has been correctly prescribed and properly administered, assign the appropriate code for the nature of the adverse effect followed by the appropriate code for the adverse effect of the drug (T36-T50). The code for the drug should have a 5th or 6th character “5” (for example T36.0X5-) Examples of the nature of an adverse effect are tachycardia, delirium, gastrointestinal hemorrhaging, vomiting, hypokalemia, hepatitis, renal failure, or respiratory failure.

Poisoning

When coding a poisoning or reaction to the improper use of a medication (e.g., overdose, wrong substance given or taken in error, wrong route of administration), first assign the appropriate code from categories T36-T50. The poisoning codes have an associated intent as their 5th or 6th character (accidental, intentional self-harm, assault and undetermined. If the intent of the poisoning is unknown or unspecified, code the intent as accidental intent. The undetermined intent is only for use if the documentation in the record specifies that the intent cannot be determined. Use additional code(s) for all manifestations of poisonings.

If there is also a diagnosis of abuse or dependence of the substance, the abuse or dependence is assigned as an additional code.

Examples of poisoning include:
  • Error was made in drug prescription
    Errors made in drug prescription or in the administration of the drug by provider, nurse, patient, or other person.
  • Overdose of a drug intentionally taken
    If an overdose of a drug was intentionally taken or administered and resulted in drug toxicity, it would be coded as a poisoning.
  • Nonprescribed drug taken with correctly prescribed and properly administered drug
    If a nonprescribed drug or medicinal agent was taken in combination with a correctly prescribed and properly administered drug, any drug toxicity or other reaction resulting from the interaction of the two drugs would be classified as a poisoning.
  • Interaction of drug(s) and alcohol
    When a reaction results from the interaction of a drug(s) and alcohol, this would be classified as poisoning.
Underdosing

Underdosing refers to taking less of a medication than is prescribed by a provider or a manufacturer's instruction. Discontinuing the use of a prescribed medication on the patient's own initiative (not directed by the patient's provider) is also classified as an underdosing. For underdosing, assign the code from categories T36-T50 (fifth or sixth character “6”).

Codes for underdosing should never be assigned as principal or first-listed codes. If a patient has a relapse or exacerbation of the medical condition for which the drug is prescribed because of the reduction in dose, then the medical condition itself should be coded.

Noncompliance (Z91.12-, Z91.13- and Z91.14-) or complication of care (Y63.6-Y63.9) codes are to be used with an underdosing code to indicate intent, if known.

Toxic Effects

When a harmful substance is ingested or comes in contact with a person, this is classified as a toxic effect. The toxic effect codes are in categories T51-T65.

Toxic effect codes have an associated intent: accidental, intentional self-harm, assault and undetermined.