The drug giving rise to the adverse effect should be identified by use of codes from categories T36-T50 with fifth or sixth character 5.

Use additional code(s) to specify:
manifestations of poisoning
underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
underdosing of medication regimen (Z91.12-, Z91.13-)

Code first  , for adverse effects, the nature of the adverse effect, such as:
  adverse effect NOS (T88.7)
  aspirin gastritis (K29.-)
  blood disorders (D56-D76)
  contact dermatitis (L23-L25)
  dermatitis due to substances taken internally (L27.-)
  nephropathy (N14.0-N14.2)

Includes:

  • adverse effect of correct substance properly administered
  • poisoning by overdose of substance
  • poisoning by wrong substance given or taken in error
  • underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed

Excludes1

  • toxic reaction to local anesthesia in pregnancy (O29.3-)

Excludes2

  • abuse and dependence of psychoactive substances (F10-F19)
  • abuse of non-dependence-producing substances (F55.-)
  • immunodeficiency due to drugs (D84.821)
  • drug reaction and poisoning affecting newborn (P00-P96)
  • pathological drug intoxication (inebriation) (F10-F19)
  1. T39 Poisoning by, adverse effect of and underdosing of nonopioid analgesics, antipyretics and antirheumatics

    The appropriate 7th character is to be added to each code from category T39

    • A - initial encounter
    • D - subsequent encounter
    • S - sequela
    1. T39.0 Poisoning by, adverse effect of and underdosing of salicylates

      1. T39.01 Poisoning by, adverse effect of and underdosing of aspirin

        Inclusion term(s):

        • Poisoning by, adverse effect of and underdosing of acetylsalicylic acid
        • T39.011 Poisoning by aspirin, accidental (unintentional)
        • T39.012 Poisoning by aspirin, intentional self-harm
        • T39.013 Poisoning by aspirin, assault
        • T39.014 Poisoning by aspirin, undetermined
        • T39.015 Adverse effect of aspirin
        • T39.016 Underdosing of aspirin
      2. T39.09 Poisoning by, adverse effect of and underdosing of other salicylates

        • T39.091 Poisoning by salicylates, accidental (unintentional)

          Inclusion term(s):

          • Poisoning by salicylates NOS
        • T39.092 Poisoning by salicylates, intentional self-harm
        • T39.093 Poisoning by salicylates, assault
        • T39.094 Poisoning by salicylates, undetermined
        • T39.095 Adverse effect of salicylates
        • T39.096 Underdosing of salicylates
    2. T39.1 Poisoning by, adverse effect of and underdosing of 4-Aminophenol derivatives

      1. T39.1X Poisoning by, adverse effect of and underdosing of 4-Aminophenol derivatives

        • T39.1X1 Poisoning by 4-Aminophenol derivatives, accidental (unintentional)

          Inclusion term(s):

          • Poisoning by 4-Aminophenol derivatives NOS
        • T39.1X2 Poisoning by 4-Aminophenol derivatives, intentional self-harm
        • T39.1X3 Poisoning by 4-Aminophenol derivatives, assault
        • T39.1X4 Poisoning by 4-Aminophenol derivatives, undetermined
        • T39.1X5 Adverse effect of 4-Aminophenol derivatives
        • T39.1X6 Underdosing of 4-Aminophenol derivatives
    3. T39.2 Poisoning by, adverse effect of and underdosing of pyrazolone derivatives

      1. T39.2X Poisoning by, adverse effect of and underdosing of pyrazolone derivatives

        • T39.2X1 Poisoning by pyrazolone derivatives, accidental (unintentional)

          Inclusion term(s):

          • Poisoning by pyrazolone derivatives NOS
        • T39.2X2 Poisoning by pyrazolone derivatives, intentional self-harm
        • T39.2X3 Poisoning by pyrazolone derivatives, assault
        • T39.2X4 Poisoning by pyrazolone derivatives, undetermined
        • T39.2X5 Adverse effect of pyrazolone derivatives
        • T39.2X6 Underdosing of pyrazolone derivatives
    4. T39.3 Poisoning by, adverse effect of and underdosing of other nonsteroidal anti-inflammatory drugs [NSAID]

      1. T39.31 Poisoning by, adverse effect of and underdosing of propionic acid derivatives

        Inclusion term(s):

        • Poisoning by, adverse effect of and underdosing of fenoprofen
        • Poisoning by, adverse effect of and underdosing of flurbiprofen
        • Poisoning by, adverse effect of and underdosing of ibuprofen
        • Poisoning by, adverse effect of and underdosing of ketoprofen
        • Poisoning by, adverse effect of and underdosing of naproxen
        • Poisoning by, adverse effect of and underdosing of oxaprozin
        • T39.311 Poisoning by propionic acid derivatives, accidental (unintentional)
        • T39.312 Poisoning by propionic acid derivatives, intentional self-harm
        • T39.313 Poisoning by propionic acid derivatives, assault
        • T39.314 Poisoning by propionic acid derivatives, undetermined
        • T39.315 Adverse effect of propionic acid derivatives
        • T39.316 Underdosing of propionic acid derivatives
      2. T39.39 Poisoning by, adverse effect of and underdosing of other nonsteroidal anti-inflammatory drugs [NSAID]

        • T39.391 Poisoning by other nonsteroidal anti-inflammatory drugs [NSAID], accidental (unintentional)

          Inclusion term(s):

          • Poisoning by other nonsteroidal anti-inflammatory drugs NOS
        • T39.392 Poisoning by other nonsteroidal anti-inflammatory drugs [NSAID], intentional self-harm
        • T39.393 Poisoning by other nonsteroidal anti-inflammatory drugs [NSAID], assault
        • T39.394 Poisoning by other nonsteroidal anti-inflammatory drugs [NSAID], undetermined
        • T39.395 Adverse effect of other nonsteroidal anti-inflammatory drugs [NSAID]
        • T39.396 Underdosing of other nonsteroidal anti-inflammatory drugs [NSAID]
    5. T39.4 Poisoning by, adverse effect of and underdosing of antirheumatics, not elsewhere classified

      1. T39.4X Poisoning by, adverse effect of and underdosing of antirheumatics, not elsewhere classified

        • T39.4X1 Poisoning by antirheumatics, not elsewhere classified, accidental (unintentional)

          Inclusion term(s):

          • Poisoning by antirheumatics, not elsewhere classified NOS
        • T39.4X2 Poisoning by antirheumatics, not elsewhere classified, intentional self-harm
        • T39.4X3 Poisoning by antirheumatics, not elsewhere classified, assault
        • T39.4X4 Poisoning by antirheumatics, not elsewhere classified, undetermined
        • T39.4X5 Adverse effect of antirheumatics, not elsewhere classified
        • T39.4X6 Underdosing of antirheumatics, not elsewhere classified
    6. T39.8 Poisoning by, adverse effect of and underdosing of other nonopioid analgesics and antipyretics, not elsewhere classified

      1. T39.8X Poisoning by, adverse effect of and underdosing of other nonopioid analgesics and antipyretics, not elsewhere classified

        • T39.8X1 Poisoning by other nonopioid analgesics and antipyretics, not elsewhere classified, accidental (unintentional)

          Inclusion term(s):

          • Poisoning by other nonopioid analgesics and antipyretics, not elsewhere classified NOS
        • T39.8X2 Poisoning by other nonopioid analgesics and antipyretics, not elsewhere classified, intentional self-harm
        • T39.8X3 Poisoning by other nonopioid analgesics and antipyretics, not elsewhere classified, assault
        • T39.8X4 Poisoning by other nonopioid analgesics and antipyretics, not elsewhere classified, undetermined
        • T39.8X5 Adverse effect of other nonopioid analgesics and antipyretics, not elsewhere classified
        • T39.8X6 Underdosing of other nonopioid analgesics and antipyretics, not elsewhere classified
    7. T39.9 Poisoning by, adverse effect of and underdosing of unspecified nonopioid analgesic, antipyretic and antirheumatic

      1. T39.91 Poisoning by unspecified nonopioid analgesic, antipyretic and antirheumatic, accidental (unintentional)

        Inclusion term(s):

        • Poisoning by nonopioid analgesic, antipyretic and antirheumatic NOS
      2. T39.92 Poisoning by unspecified nonopioid analgesic, antipyretic and antirheumatic, intentional self-harm

      3. T39.93 Poisoning by unspecified nonopioid analgesic, antipyretic and antirheumatic, assault

      4. T39.94 Poisoning by unspecified nonopioid analgesic, antipyretic and antirheumatic, undetermined

      5. T39.95 Adverse effect of unspecified nonopioid analgesic, antipyretic and antirheumatic

      6. T39.96 Underdosing of unspecified nonopioid analgesic, antipyretic and antirheumatic

Abbreviations used here:

NEC Not elsewhere classifiable
This abbreviation in the Tabular List represents “other specified”. When a specific code is not available for a condition, the Tabular List includes an NEC entry under a code to identify the code as the “other specified” code.

NOS Not otherwise specified
This abbreviation is the equivalent of unspecified.