1. Z16 Resistance to antimicrobial drugs

    Note: The codes in this category are provided for use as additional codes to identify the resistance and non-responsiveness of a condition to antimicrobial drugs.

    Excludes1

    • Methicillin resistant Staphylococcus aureus infection (A49.02)
    • Methicillin resistant Staphylococcus aureus pneumonia (J15.212)
    • Sepsis due to Methicillin resistant Staphylococcus aureus (A41.02)
    1. Z16.1 Resistance to beta lactam antibiotics

      1. Z16.10 Resistance to unspecified beta lactam antibiotics

      2. Z16.11 Resistance to penicillins

        Inclusion term(s):

        • Resistance to amoxicillin
        • Resistance to ampicillin
      3. Z16.12 Extended spectrum beta lactamase (ESBL) resistance

      4. Z16.13 Resistance to carbapenem

      5. Z16.19 Resistance to other specified beta lactam antibiotics

        Inclusion term(s):

        • Resistance to cephalosporins
    2. Z16.2 Resistance to other antibiotics

      1. Z16.20 Resistance to unspecified antibiotic

        Inclusion term(s):

        • Resistance to antibiotics NOS
      2. Z16.21 Resistance to vancomycin

      3. Z16.22 Resistance to vancomycin related antibiotics

      4. Z16.23 Resistance to quinolones and fluoroquinolones

      5. Z16.24 Resistance to multiple antibiotics

      6. Z16.29 Resistance to other single specified antibiotic

        Inclusion term(s):

        • Resistance to aminoglycosides
        • Resistance to macrolides
        • Resistance to sulfonamides
        • Resistance to tetracyclines
    3. Z16.3 Resistance to other antimicrobial drugs

      1. Z16.30 Resistance to unspecified antimicrobial drugs

        Inclusion term(s):

        • Drug resistance NOS
      2. Z16.31 Resistance to antiparasitic drug(s)

        Inclusion term(s):

        • Resistance to quinine and related compounds
      3. Z16.32 Resistance to antifungal drug(s)

      4. Z16.33 Resistance to antiviral drug(s)

      5. Z16.34 Resistance to antimycobacterial drug(s)

        Inclusion term(s):

        • Resistance to tuberculostatics
        • Z16.341 Resistance to single antimycobacterial drug

          Inclusion term(s):

          • Resistance to antimycobacterial drug NOS
        • Z16.342 Resistance to multiple antimycobacterial drugs
      6. Z16.35 Resistance to multiple antimicrobial drugs

      7. Z16.39 Resistance to other specified antimicrobial drug

Abbreviations used here:

NEC Not elsewhere classifiable
This abbreviation in the Tabular List represents “other specified”. When a specific code is not available for a condition, the Tabular List includes an NEC entry under a code to identify the code as the “other specified” code.

NOS Not otherwise specified
This abbreviation is the equivalent of unspecified.