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Substance Poisoning
Accidental (unintentional)
Poisoning
Intentional (self-harm)
Poisoning
Assault
Poisoning
Undetermined
Adverse
Effect
Underdosing
2-Ethoxyethanol T52.3X1 T52.3X2 T52.3X3 T52.3X4 -- --
Ethoxzolamide T50.2X1 T50.2X2 T50.2X3 T50.2X4 T50.2X5 T50.2X6
Ethyl
– acetate T52.8X1 T52.8X2 T52.8X3 T52.8X4 -- --
– alcohol T51.0X1 T51.0X2 T51.0X3 T51.0X4 -- --
– – beverage T51.0X1 T51.0X2 T51.0X3 T51.0X4 -- --
– aldehyde (vapor) T59.891 T59.892 T59.893 T59.894 -- --
– – liquid T52.8X1 T52.8X2 T52.8X3 T52.8X4 -- --
– aminobenzoate T41.3X1 T41.3X2 T41.3X3 T41.3X4 T41.3X5 T41.3X6
– aminophenothiazine T43.3X1 T43.3X2 T43.3X3 T43.3X4 T43.3X5 T43.3X6
– benzoate T52.8X1 T52.8X2 T52.8X3 T52.8X4 -- --
– biscoumacetate T45.511 T45.512 T45.513 T45.514 T45.515 T45.516
– bromide (anesthetic) T41.0X1 T41.0X2 T41.0X3 T41.0X4 T41.0X5 T41.0X6
– carbamate T45.1X1 T45.1X2 T45.1X3 T45.1X4 T45.1X5 T45.1X6
– carbinol T51.3X1 T51.3X2 T51.3X3 T51.3X4 -- --
– carbonate T52.8X1 T52.8X2 T52.8X3 T52.8X4 -- --
– chaulmoograte T37.1X1 T37.1X2 T37.1X3 T37.1X4 T37.1X5 T37.1X6
– chloride (anesthetic) T41.0X1 T41.0X2 T41.0X3 T41.0X4 T41.0X5 T41.0X6
– – anesthetic (local) T41.3X1 T41.3X2 T41.3X3 T41.3X4 T41.3X5 T41.3X6
– – – inhaled T41.0X1 T41.0X2 T41.0X3 T41.0X4 T41.0X5 T41.0X6
– – local T49.4X1 T49.4X2 T49.4X3 T49.4X4 T49.4X5 T49.4X6
– – solvent T53.6X1 T53.6X2 T53.6X3 T53.6X4 -- --
– dibunate T48.3X1 T48.3X2 T48.3X3 T48.3X4 T48.3X5 T48.3X6
– dichloroarsine (vapor) T57.0X1 T57.0X2 T57.0X3 T57.0X4 -- --
– estranol T38.7X1 T38.7X2 T38.7X3 T38.7X4 T38.7X5 T38.7X6
– ether   see also ether T52.8X1 T52.8X2 T52.8X3 T52.8X4 -- --
– formate NEC (solvent) T52.0X1 T52.0X2 T52.0X3 T52.0X4 -- --
– fumarate T49.4X1 T49.4X2 T49.4X3 T49.4X4 T49.4X5 T49.4X6
– hydroxyisobutyrate NEC (solvent) T52.8X1 T52.8X2 T52.8X3 T52.8X4 -- --
– iodoacetate T59.3X1 T59.3X2 T59.3X3 T59.3X4 -- --
– lactate NEC (solvent) T52.8X1 T52.8X2 T52.8X3 T52.8X4 -- --
– loflazepate T42.4X1 T42.4X2 T42.4X3 T42.4X4 T42.4X5 T42.4X6
– mercuric chloride T56.1X1 T56.1X2 T56.1X3 T56.1X4 -- --
– methylcarbinol T51.8X1 T51.8X2 T51.8X3 T51.8X4 -- --
– morphine T40.2X1 T40.2X2 T40.2X3 T40.2X4 T40.2X5 T40.2X6
– noradrenaline T48.6X1 T48.6X2 T48.6X3 T48.6X4 T48.6X5 T48.6X6
– oxybutyrate NEC (solvent) T52.8X1 T52.8X2 T52.8X3 T52.8X4 -- --
Ethylene (gas) T59.891 T59.892 T59.893 T59.894 -- --
– anesthetic (general) T41.0X1 T41.0X2 T41.0X3 T41.0X4 T41.0X5 T41.0X6
– chlorohydrin T52.8X1 T52.8X2 T52.8X3 T52.8X4 -- --
– – vapor T53.6X1 T53.6X2 T53.6X3 T53.6X4 -- --
– dichloride T52.8X1 T52.8X2 T52.8X3 T52.8X4 -- --
– – vapor T53.6X1 T53.6X2 T53.6X3 T53.6X4 -- --
– dinitrate T52.3X1 T52.3X2 T52.3X3 T52.3X4 -- --
– glycol (s) T52.8X1 T52.8X2 T52.8X3 T52.8X4 -- --
– – dinitrate T52.3X1 T52.3X2 T52.3X3 T52.3X4 -- --
– – monobutyl ether T52.3X1 T52.3X2 T52.3X3 T52.3X4 -- --
– imine T54.1X1 T54.1X2 T54.1X3 T54.1X4 -- --
– oxide (fumigant) (nonmedicinal) T59.891 T59.892 T59.893 T59.894 -- --
– – medicinal T49.0X1 T49.0X2 T49.0X3 T49.0X4 T49.0X5 T49.0X6
Ethylenediamine theophylline T48.6X1 T48.6X2 T48.6X3 T48.6X4 T48.6X5 T48.6X6
Ethylenediaminetetra-acetic acid T50.6X1 T50.6X2 T50.6X3 T50.6X4 T50.6X5 T50.6X6
Ethylenedinitrilotetra-acetate T50.6X1 T50.6X2 T50.6X3 T50.6X4 T50.6X5 T50.6X6
Ethylestrenol T38.7X1 T38.7X2 T38.7X3 T38.7X4 T38.7X5 T38.7X6
Ethylhydroxycellulose T47.4X1 T47.4X2 T47.4X3 T47.4X4 T47.4X5 T47.4X6
Ethylidene
– chloride NEC T53.6X1 T53.6X2 T53.6X3 T53.6X4 -- --
– diacetate T60.3X1 T60.3X2 T60.3X3 T60.3X4 -- --
– dicoumarin T45.511 T45.512 T45.513 T45.514 T45.515 T45.516
– dicoumarol T45.511 T45.512 T45.513 T45.514 T45.515 T45.516
– diethyl ether T52.0X1 T52.0X2 T52.0X3 T52.0X4 -- --

The occurrence of drug toxicity is classified in ICD-10-CM as follows:

Adverse Effect

When coding an adverse effect of a drug that has been correctly prescribed and properly administered, assign the appropriate code for the nature of the adverse effect followed by the appropriate code for the adverse effect of the drug (T36-T50). The code for the drug should have a 5th or 6th character “5” (for example T36.0X5-) Examples of the nature of an adverse effect are tachycardia, delirium, gastrointestinal hemorrhaging, vomiting, hypokalemia, hepatitis, renal failure, or respiratory failure.

Poisoning

When coding a poisoning or reaction to the improper use of a medication (e.g., overdose, wrong substance given or taken in error, wrong route of administration), first assign the appropriate code from categories T36-T50. The poisoning codes have an associated intent as their 5th or 6th character (accidental, intentional self-harm, assault and undetermined. If the intent of the poisoning is unknown or unspecified, code the intent as accidental intent. The undetermined intent is only for use if the documentation in the record specifies that the intent cannot be determined. Use additional code(s) for all manifestations of poisonings.

If there is also a diagnosis of abuse or dependence of the substance, the abuse or dependence is assigned as an additional code.

Examples of poisoning include:
  • Error was made in drug prescription
    Errors made in drug prescription or in the administration of the drug by provider, nurse, patient, or other person.
  • Overdose of a drug intentionally taken
    If an overdose of a drug was intentionally taken or administered and resulted in drug toxicity, it would be coded as a poisoning.
  • Nonprescribed drug taken with correctly prescribed and properly administered drug
    If a nonprescribed drug or medicinal agent was taken in combination with a correctly prescribed and properly administered drug, any drug toxicity or other reaction resulting from the interaction of the two drugs would be classified as a poisoning.
  • Interaction of drug(s) and alcohol
    When a reaction results from the interaction of a drug(s) and alcohol, this would be classified as poisoning.
Underdosing

Underdosing refers to taking less of a medication than is prescribed by a provider or a manufacturer's instruction. Discontinuing the use of a prescribed medication on the patient's own initiative (not directed by the patient's provider) is also classified as an underdosing. For underdosing, assign the code from categories T36-T50 (fifth or sixth character “6”).

Codes for underdosing should never be assigned as principal or first-listed codes. If a patient has a relapse or exacerbation of the medical condition for which the drug is prescribed because of the reduction in dose, then the medical condition itself should be coded.

Noncompliance (Z91.12-, Z91.13- and Z91.14-) or complication of care (Y63.6-Y63.9) codes are to be used with an underdosing code to indicate intent, if known.

Toxic Effects

When a harmful substance is ingested or comes in contact with a person, this is classified as a toxic effect. The toxic effect codes are in categories T51-T65.

Toxic effect codes have an associated intent: accidental, intentional self-harm, assault and undetermined.