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Substance Poisoning
Accidental (unintentional)
Poisoning
Intentional (self-harm)
Poisoning
Assault
Poisoning
Undetermined
Adverse
Effect
Underdosing
Amiquinsin T46.5X1 T46.5X2 T46.5X3 T46.5X4 T46.5X5 T46.5X6
Amisometradine T50.2X1 T50.2X2 T50.2X3 T50.2X4 T50.2X5 T50.2X6
Amisulpride T43.591 T43.592 T43.593 T43.594 T43.595 T43.596
Amitriptyline T43.011 T43.012 T43.013 T43.014 T43.015 T43.016
Amitriptylinoxide T43.011 T43.012 T43.013 T43.014 T43.015 T43.016
Amlexanox T48.6X1 T48.6X2 T48.6X3 T48.6X4 T48.6X5 T48.6X6
Ammonia (fumes) (gas) (vapor) T59.891 T59.892 T59.893 T59.894 -- --
– aromatic spirit T48.991 T48.992 T48.993 T48.994 T48.995 T48.996
– liquid (household) T54.3X1 T54.3X2 T54.3X3 T54.3X4 -- --
Ammoniated mercury T49.0X1 T49.0X2 T49.0X3 T49.0X4 T49.0X5 T49.0X6
Ammonium
– acid tartrate T49.5X1 T49.5X2 T49.5X3 T49.5X4 T49.5X5 T49.5X6
– bromide T42.6X1 T42.6X2 T42.6X3 T42.6X4 T42.6X5 T42.6X6
– carbonate T54.3X1 T54.3X2 T54.3X3 T54.3X4 -- --
– chloride T50.991 T50.992 T50.993 T50.994 T50.995 T50.996
– – expectorant T48.4X1 T48.4X2 T48.4X3 T48.4X4 T48.4X5 T48.4X6
– compounds (household) T54.3X1 T54.3X2 T54.3X3 T54.3X4 -- --
– – fumes (any usage) T59.891 T59.892 T59.893 T59.894 -- --
– – industrial T54.3X1 T54.3X2 T54.3X3 T54.3X4 -- --
– ichthyosulronate T49.4X1 T49.4X2 T49.4X3 T49.4X4 T49.4X5 T49.4X6
– mandelate T37.91 T37.92 T37.93 T37.94 T37.95 T37.96
– sulfamate T60.3X1 T60.3X2 T60.3X3 T60.3X4 -- --
– sulfonate resin T47.8X1 T47.8X2 T47.8X3 T47.8X4 T47.8X5 T47.8X6
Amobarbital (sodium) T42.3X1 T42.3X2 T42.3X3 T42.3X4 T42.3X5 T42.3X6

The occurrence of drug toxicity is classified in ICD-10-CM as follows:

Adverse Effect

When coding an adverse effect of a drug that has been correctly prescribed and properly administered, assign the appropriate code for the nature of the adverse effect followed by the appropriate code for the adverse effect of the drug (T36-T50). The code for the drug should have a 5th or 6th character “5” (for example T36.0X5-) Examples of the nature of an adverse effect are tachycardia, delirium, gastrointestinal hemorrhaging, vomiting, hypokalemia, hepatitis, renal failure, or respiratory failure.

Poisoning

When coding a poisoning or reaction to the improper use of a medication (e.g., overdose, wrong substance given or taken in error, wrong route of administration), first assign the appropriate code from categories T36-T50. The poisoning codes have an associated intent as their 5th or 6th character (accidental, intentional self-harm, assault and undetermined. If the intent of the poisoning is unknown or unspecified, code the intent as accidental intent. The undetermined intent is only for use if the documentation in the record specifies that the intent cannot be determined. Use additional code(s) for all manifestations of poisonings.

If there is also a diagnosis of abuse or dependence of the substance, the abuse or dependence is assigned as an additional code.

Examples of poisoning include:
  • Error was made in drug prescription
    Errors made in drug prescription or in the administration of the drug by provider, nurse, patient, or other person.
  • Overdose of a drug intentionally taken
    If an overdose of a drug was intentionally taken or administered and resulted in drug toxicity, it would be coded as a poisoning.
  • Nonprescribed drug taken with correctly prescribed and properly administered drug
    If a nonprescribed drug or medicinal agent was taken in combination with a correctly prescribed and properly administered drug, any drug toxicity or other reaction resulting from the interaction of the two drugs would be classified as a poisoning.
  • Interaction of drug(s) and alcohol
    When a reaction results from the interaction of a drug(s) and alcohol, this would be classified as poisoning.
Underdosing

Underdosing refers to taking less of a medication than is prescribed by a provider or a manufacturer's instruction. Discontinuing the use of a prescribed medication on the patient's own initiative (not directed by the patient's provider) is also classified as an underdosing. For underdosing, assign the code from categories T36-T50 (fifth or sixth character “6”).

Codes for underdosing should never be assigned as principal or first-listed codes. If a patient has a relapse or exacerbation of the medical condition for which the drug is prescribed because of the reduction in dose, then the medical condition itself should be coded.

Noncompliance (Z91.12-, Z91.13- and Z91.14-) or complication of care (Y63.6-Y63.9) codes are to be used with an underdosing code to indicate intent, if known.

Toxic Effects

When a harmful substance is ingested or comes in contact with a person, this is classified as a toxic effect. The toxic effect codes are in categories T51-T65.

Toxic effect codes have an associated intent: accidental, intentional self-harm, assault and undetermined.