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Substance Poisoning
Accidental (unintentional)
Poisoning
Intentional (self-harm)
Poisoning
Assault
Poisoning
Undetermined
Adverse
Effect
Underdosing
Soap (powder) (product) T55.0X1 T55.0X2 T55.0X3 T55.0X4 -- --
– enema T47.4X1 T47.4X2 T47.4X3 T47.4X4 T47.4X5 T47.4X6
– medicinal, soft T49.2X1 T49.2X2 T49.2X3 T49.2X4 T49.2X5 T49.2X6
– superfatted T49.2X1 T49.2X2 T49.2X3 T49.2X4 T49.2X5 T49.2X6
Sobrerol T48.4X1 T48.4X2 T48.4X3 T48.4X4 T48.4X5 T48.4X6
Soda (caustic) T54.3X1 T54.3X2 T54.3X3 T54.3X4 -- --
– bicarb T47.1X1 T47.1X2 T47.1X3 T47.1X4 T47.1X5 T47.1X6
Sodium
– acetosulfone T37.1X1 T37.1X2 T37.1X3 T37.1X4 T37.1X5 T37.1X6
– acetrizoate T50.8X1 T50.8X2 T50.8X3 T50.8X4 T50.8X5 T50.8X6
– acid phosphate T50.3X1 T50.3X2 T50.3X3 T50.3X4 T50.3X5 T50.3X6
– alginate T47.8X1 T47.8X2 T47.8X3 T47.8X4 T47.8X5 T47.8X6
– amidotrizoate T50.8X1 T50.8X2 T50.8X3 T50.8X4 T50.8X5 T50.8X6
– aminopterin T45.1X1 T45.1X2 T45.1X3 T45.1X4 T45.1X5 T45.1X6
– amylosulfate T47.8X1 T47.8X2 T47.8X3 T47.8X4 T47.8X5 T47.8X6
– amytal T42.3X1 T42.3X2 T42.3X3 T42.3X4 T42.3X5 T42.3X6
– antimony gluconate T37.3X1 T37.3X2 T37.3X3 T37.3X4 T37.3X5 T37.3X6
– arsenate T57.0X1 T57.0X2 T57.0X3 T57.0X4 -- --
– aurothiomalate T39.4X1 T39.4X2 T39.4X3 T39.4X4 T39.4X5 T39.4X6
– aurothiosulfate T39.4X1 T39.4X2 T39.4X3 T39.4X4 T39.4X5 T39.4X6
– barbiturate T42.3X1 T42.3X2 T42.3X3 T42.3X4 T42.3X5 T42.3X6
– basic phosphate T47.4X1 T47.4X2 T47.4X3 T47.4X4 T47.4X5 T47.4X6
– bicarbonate T47.1X1 T47.1X2 T47.1X3 T47.1X4 T47.1X5 T47.1X6
– bichromate T57.8X1 T57.8X2 T57.8X3 T57.8X4 -- --
– biphosphate T50.3X1 T50.3X2 T50.3X3 T50.3X4 T50.3X5 T50.3X6
– bisulfate T65.891 T65.892 T65.893 T65.894 -- --
– – cleanser T57.8X1 T57.8X2 T57.8X3 T57.8X4 -- --
– – – eye T49.5X1 T49.5X2 T49.5X3 T49.5X4 T49.5X5 T49.5X6
– – therapeutic T49.8X1 T49.8X2 T49.8X3 T49.8X4 T49.8X5 T49.8X6
– bromide T42.6X1 T42.6X2 T42.6X3 T42.6X4 T42.6X5 T42.6X6
– cacodylate (nonmedicinal) T50.8X1 T50.8X2 T50.8X3 T50.8X4 T50.8X5 T50.8X6
– – anti-infective T37.8X1 T37.8X2 T37.8X3 T37.8X4 T37.8X5 T37.8X6
– – herbicide T60.3X1 T60.3X2 T60.3X3 T60.3X4 -- --
– calcium edetate T45.8X1 T45.8X2 T45.8X3 T45.8X4 T45.8X5 T45.8X6
– carbonate NEC T54.3X1 T54.3X2 T54.3X3 T54.3X4 -- --
– chlorate NEC T65.891 T65.892 T65.893 T65.894 -- --
– – herbicide T54.91 T54.92 T54.93 T54.94 -- --
– chloride T50.3X1 T50.3X2 T50.3X3 T50.3X4 T50.3X5 T50.3X6
– – with glucose T50.3X1 T50.3X2 T50.3X3 T50.3X4 T50.3X5 T50.3X6
– chromate T65.891 T65.892 T65.893 T65.894 -- --
– citrate T50.991 T50.992 T50.993 T50.994 T50.995 T50.996
– cromoglicate T48.6X1 T48.6X2 T48.6X3 T48.6X4 T48.6X5 T48.6X6
– cyanide T65.0X1 T65.0X2 T65.0X3 T65.0X4 -- --
– cyclamate T50.3X1 T50.3X2 T50.3X3 T50.3X4 T50.3X5 T50.3X6
– dehydrocholate T45.8X1 T45.8X2 T45.8X3 T45.8X4 T45.8X5 T45.8X6
– diatrizoate T50.8X1 T50.8X2 T50.8X3 T50.8X4 T50.8X5 T50.8X6
– dibunate T48.4X1 T48.4X2 T48.4X3 T48.4X4 T48.4X5 T48.4X6
– dioctyl sulfosuccinate T47.4X1 T47.4X2 T47.4X3 T47.4X4 T47.4X5 T47.4X6
– dipantoyl ferrate T45.8X1 T45.8X2 T45.8X3 T45.8X4 T45.8X5 T45.8X6
– edetate T45.8X1 T45.8X2 T45.8X3 T45.8X4 T45.8X5 T45.8X6
– ethacrynate T50.1X1 T50.1X2 T50.1X3 T50.1X4 T50.1X5 T50.1X6
– feredetate T45.8X1 T45.8X2 T45.8X3 T45.8X4 T45.8X5 T45.8X6
– fluoroacetate (dust) (pesticide) T60.4X1 T60.4X2 T60.4X3 T60.4X4 -- --
– free salt T50.3X1 T50.3X2 T50.3X3 T50.3X4 T50.3X5 T50.3X6
– fusidate T36.8X1 T36.8X2 T36.8X3 T36.8X4 T36.8X5 T36.8X6
– glucaldrate T47.1X1 T47.1X2 T47.1X3 T47.1X4 T47.1X5 T47.1X6
– glucosulfone T37.1X1 T37.1X2 T37.1X3 T37.1X4 T37.1X5 T37.1X6
– glutamate T45.8X1 T45.8X2 T45.8X3 T45.8X4 T45.8X5 T45.8X6
– hydrogen carbonate T50.3X1 T50.3X2 T50.3X3 T50.3X4 T50.3X5 T50.3X6
– hydroxide T54.3X1 T54.3X2 T54.3X3 T54.3X4 -- --
– hypochlorite (bleach) T54.3X1 T54.3X2 T54.3X3 T54.3X4 -- --
– – disinfectant T54.3X1 T54.3X2 T54.3X3 T54.3X4 -- --
– – medicinal (anti-infective) (external) T49.0X1 T49.0X2 T49.0X3 T49.0X4 T49.0X5 T49.0X6
– – vapor T54.3X1 T54.3X2 T54.3X3 T54.3X4 -- --
– hyposulfite T49.0X1 T49.0X2 T49.0X3 T49.0X4 T49.0X5 T49.0X6
– indigotin disulfonate T50.8X1 T50.8X2 T50.8X3 T50.8X4 T50.8X5 T50.8X6
– iodide T50.991 T50.992 T50.993 T50.994 T50.995 T50.996
– – I-131 T50.8X1 T50.8X2 T50.8X3 T50.8X4 T50.8X5 T50.8X6
– – – therapeutic T38.2X1 T38.2X2 T38.2X3 T38.2X4 T38.2X5 T38.2X6
– iodohippurate (131I) T50.8X1 T50.8X2 T50.8X3 T50.8X4 T50.8X5 T50.8X6
– iopodate T50.8X1 T50.8X2 T50.8X3 T50.8X4 T50.8X5 T50.8X6
– iothalamate T50.8X1 T50.8X2 T50.8X3 T50.8X4 T50.8X5 T50.8X6
– iron edetate T45.4X1 T45.4X2 T45.4X3 T45.4X4 T45.4X5 T45.4X6
– lactate (compound solution) T45.8X1 T45.8X2 T45.8X3 T45.8X4 T45.8X5 T45.8X6
– lauryl (sulfate) T49.2X1 T49.2X2 T49.2X3 T49.2X4 T49.2X5 T49.2X6
– L-triiodothyronine T38.1X1 T38.1X2 T38.1X3 T38.1X4 T38.1X5 T38.1X6
– magnesium citrate T50.991 T50.992 T50.993 T50.994 T50.995 T50.996
– mersalate T50.2X1 T50.2X2 T50.2X3 T50.2X4 T50.2X5 T50.2X6
– metasilicate T65.891 T65.892 T65.893 T65.894 -- --
– metrizoate T50.8X1 T50.8X2 T50.8X3 T50.8X4 T50.8X5 T50.8X6
– monofluoroacetate (pesticide) T60.1X1 T60.1X2 T60.1X3 T60.1X4 -- --
– morrhuate T46.8X1 T46.8X2 T46.8X3 T46.8X4 T46.8X5 T46.8X6
– nafcillin T36.0X1 T36.0X2 T36.0X3 T36.0X4 T36.0X5 T36.0X6
– nitrate (oxidizing agent) T65.891 T65.892 T65.893 T65.894 -- --
– nitrite T50.6X1 T50.6X2 T50.6X3 T50.6X4 T50.6X5 T50.6X6
– nitroferricyanide T46.5X1 T46.5X2 T46.5X3 T46.5X4 T46.5X5 T46.5X6
– nitroprusside T46.5X1 T46.5X2 T46.5X3 T46.5X4 T46.5X5 T46.5X6
– oxalate T65.891 T65.892 T65.893 T65.894 -- --
– oxide/peroxide T65.891 T65.892 T65.893 T65.894 -- --
– oxybate T41.291 T41.292 T41.293 T41.294 T41.295 T41.296
– para-aminohippurate T50.8X1 T50.8X2 T50.8X3 T50.8X4 T50.8X5 T50.8X6
– perborate (nonmedicinal) T65.891 T65.892 T65.893 T65.894 -- --
– – medicinal T49.0X1 T49.0X2 T49.0X3 T49.0X4 T49.0X5 T49.0X6
– – soap T55.0X1 T55.0X2 T55.0X3 T55.0X4 -- --
– pertechnetate Tc99m T50.8X1 T50.8X2 T50.8X3 T50.8X4 T50.8X5 T50.8X6
– – cellulose T45.8X1 T45.8X2 T45.8X3 T45.8X4 T45.8X5 T45.8X6
– – dibasic T47.2X1 T47.2X2 T47.2X3 T47.2X4 T47.2X5 T47.2X6
– – monobasic T47.2X1 T47.2X2 T47.2X3 T47.2X4 T47.2X5 T47.2X6
– phytate T50.6X1 T50.6X2 T50.6X3 T50.6X4 T50.6X5 T50.6X6
– picosulfate T47.2X1 T47.2X2 T47.2X3 T47.2X4 T47.2X5 T47.2X6
– polyhydroxyaluminium monocarbonate T47.1X1 T47.1X2 T47.1X3 T47.1X4 T47.1X5 T47.1X6
– polystyrene sulfonate T50.3X1 T50.3X2 T50.3X3 T50.3X4 T50.3X5 T50.3X6
– propionate T49.0X1 T49.0X2 T49.0X3 T49.0X4 T49.0X5 T49.0X6
– propyl hydroxybenzoate T50.991 T50.992 T50.993 T50.994 T50.995 T50.996
– psylliate T46.8X1 T46.8X2 T46.8X3 T46.8X4 T46.8X5 T46.8X6
– removing resins T50.3X1 T50.3X2 T50.3X3 T50.3X4 T50.3X5 T50.3X6
– salicylate T39.091 T39.092 T39.093 T39.094 T39.095 T39.096
– salt NEC T50.3X1 T50.3X2 T50.3X3 T50.3X4 T50.3X5 T50.3X6
– selenate T60.2X1 T60.2X2 T60.2X3 T60.2X4 -- --
– stibogluconate T37.3X1 T37.3X2 T37.3X3 T37.3X4 T37.3X5 T37.3X6
– sulfate T47.4X1 T47.4X2 T47.4X3 T47.4X4 T47.4X5 T47.4X6
– sulfoxone T37.1X1 T37.1X2 T37.1X3 T37.1X4 T37.1X5 T37.1X6
– tetradecyl sulfate T46.8X1 T46.8X2 T46.8X3 T46.8X4 T46.8X5 T46.8X6
– thiopental T41.1X1 T41.1X2 T41.1X3 T41.1X4 T41.1X5 T41.1X6
– thiosalicylate T39.091 T39.092 T39.093 T39.094 T39.095 T39.096
– thiosulfate T50.6X1 T50.6X2 T50.6X3 T50.6X4 T50.6X5 T50.6X6
– tolbutamide T38.3X1 T38.3X2 T38.3X3 T38.3X4 T38.3X5 T38.3X6
– -triiodothyronine (L) T38.1X1 T38.1X2 T38.1X3 T38.1X4 T38.1X5 T38.1X6
– tyropanoate T50.8X1 T50.8X2 T50.8X3 T50.8X4 T50.8X5 T50.8X6
– valproate T42.6X1 T42.6X2 T42.6X3 T42.6X4 T42.6X5 T42.6X6
– versenate T50.6X1 T50.6X2 T50.6X3 T50.6X4 T50.6X5 T50.6X6
Sodium-free salt T50.901 T50.902 T50.903 T50.904 T50.905 T50.906
Sodium-removing resin T50.3X1 T50.3X2 T50.3X3 T50.3X4 T50.3X5 T50.3X6
Soft soap T55.0X1 T55.0X2 T55.0X3 T55.0X4 -- --
Solanine T62.2X1 T62.2X2 T62.2X3 T62.2X4 -- --
– berries T62.1X1 T62.1X2 T62.1X3 T62.1X4 -- --
Solanum dulcamara T62.2X1 T62.2X2 T62.2X3 T62.2X4 -- --
– berries T62.1X1 T62.1X2 T62.1X3 T62.1X4 -- --
Solapsone T37.1X1 T37.1X2 T37.1X3 T37.1X4 T37.1X5 T37.1X6

The occurrence of drug toxicity is classified in ICD-10-CM as follows:

Adverse Effect

When coding an adverse effect of a drug that has been correctly prescribed and properly administered, assign the appropriate code for the nature of the adverse effect followed by the appropriate code for the adverse effect of the drug (T36-T50). The code for the drug should have a 5th or 6th character “5” (for example T36.0X5-) Examples of the nature of an adverse effect are tachycardia, delirium, gastrointestinal hemorrhaging, vomiting, hypokalemia, hepatitis, renal failure, or respiratory failure.

Poisoning

When coding a poisoning or reaction to the improper use of a medication (e.g., overdose, wrong substance given or taken in error, wrong route of administration), first assign the appropriate code from categories T36-T50. The poisoning codes have an associated intent as their 5th or 6th character (accidental, intentional self-harm, assault and undetermined. If the intent of the poisoning is unknown or unspecified, code the intent as accidental intent. The undetermined intent is only for use if the documentation in the record specifies that the intent cannot be determined. Use additional code(s) for all manifestations of poisonings.

If there is also a diagnosis of abuse or dependence of the substance, the abuse or dependence is assigned as an additional code.

Examples of poisoning include:
  • Error was made in drug prescription
    Errors made in drug prescription or in the administration of the drug by provider, nurse, patient, or other person.
  • Overdose of a drug intentionally taken
    If an overdose of a drug was intentionally taken or administered and resulted in drug toxicity, it would be coded as a poisoning.
  • Nonprescribed drug taken with correctly prescribed and properly administered drug
    If a nonprescribed drug or medicinal agent was taken in combination with a correctly prescribed and properly administered drug, any drug toxicity or other reaction resulting from the interaction of the two drugs would be classified as a poisoning.
  • Interaction of drug(s) and alcohol
    When a reaction results from the interaction of a drug(s) and alcohol, this would be classified as poisoning.
Underdosing

Underdosing refers to taking less of a medication than is prescribed by a provider or a manufacturer's instruction. Discontinuing the use of a prescribed medication on the patient's own initiative (not directed by the patient's provider) is also classified as an underdosing. For underdosing, assign the code from categories T36-T50 (fifth or sixth character “6”).

Codes for underdosing should never be assigned as principal or first-listed codes. If a patient has a relapse or exacerbation of the medical condition for which the drug is prescribed because of the reduction in dose, then the medical condition itself should be coded.

Noncompliance (Z91.12-, Z91.13- and Z91.14-) or complication of care (Y63.6-Y63.9) codes are to be used with an underdosing code to indicate intent, if known.

Toxic Effects

When a harmful substance is ingested or comes in contact with a person, this is classified as a toxic effect. The toxic effect codes are in categories T51-T65.

Toxic effect codes have an associated intent: accidental, intentional self-harm, assault and undetermined.