ICD-10-CM — Chapter 4

Endocrine, nutritional and metabolic diseases - Use for Diabetes mellitus, nutritional deficiencies, and other metabolic and endocrine disorders not elsewhere classified.

Tabular List

Find your ICD-10-CM code by first selecting the most applicable chapter

Endocrine, nutritional and metabolic diseases

- Use for Diabetes mellitus, nutritional deficiencies, and other metabolic and endocrine disorders not elsewhere classified.

Note: All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.


  • transitory endocrine and metabolic disorders specific to newborn (P70-P74)
Expand All Chapter #4 contains the following ICD-10-CM sections:
  • E00 Congenital iodine-deficiency syndrome

  • E01 Iodine-deficiency related thyroid disorders and allied conditions

  • E02 Subclinical iodine-deficiency hypothyroidism

  • E03 Other hypothyroidism

  • E04 Other nontoxic goiter

  • E05 Thyrotoxicosis [hyperthyroidism]

  • E06 Thyroiditis

  • E07 Other disorders of thyroid

  • E08 Diabetes mellitus due to underlying condition

  • E09 Drug or chemical induced diabetes mellitus

  • E10 Type 1 diabetes mellitus

  • E11 Type 2 diabetes mellitus

  • E13 Other specified diabetes mellitus

  • E15 Nondiabetic hypoglycemic coma

  • E16 Other disorders of pancreatic internal secretion


  • E20 Hypoparathyroidism

  • E21 Hyperparathyroidism and other disorders of parathyroid gland

  • E22 Hyperfunction of pituitary gland

  • E23 Hypofunction and other disorders of the pituitary gland

  • E24 Cushing's syndrome

  • E25 Adrenogenital disorders

  • E26 Hyperaldosteronism

  • E27 Other disorders of adrenal gland

  • E28 Ovarian dysfunction

  • E29 Testicular dysfunction

  • E30 Disorders of puberty, not elsewhere classified

  • E31 Polyglandular dysfunction

  • E32 Diseases of thymus

  • E34 Other endocrine disorders

  • E35 Disorders of endocrine glands in diseases classified elsewhere

  • E36 Intraoperative complications of endocrine system


  • intestinal malabsorption (K90.-)
  • sequelae of protein-calorie malnutrition (E64.0)


  • E40 Kwashiorkor

    Inclusion term(s):

    • Severe malnutrition with nutritional edema with dyspigmentation of skin and hair
  • E41 Nutritional marasmus

    Inclusion term(s):

    • Severe malnutrition with marasmus
  • E42 Marasmic kwashiorkor

    Inclusion term(s):

    • Intermediate form severe protein-calorie malnutrition
    • Severe protein-calorie malnutrition with signs of both kwashiorkor and marasmus
  • E43 Unspecified severe protein-calorie malnutrition

    Inclusion term(s):

    • Starvation edema
  • E44 Protein-calorie malnutrition of moderate and mild degree

  • E45 Retarded development following protein-calorie malnutrition

    Inclusion term(s):

    • Nutritional short stature
    • Nutritional stunting
    • Physical retardation due to malnutrition
  • E46 Unspecified protein-calorie malnutrition

    Inclusion term(s):

    • Malnutrition NOS
    • Protein-calorie imbalance NOS


  • E50 Vitamin A deficiency

  • E51 Thiamine deficiency

  • E52 Niacin deficiency [pellagra]

    Inclusion term(s):

    • Niacin (-tryptophan) deficiency
    • Nicotinamide deficiency
    • Pellagra (alcoholic)
  • E53 Deficiency of other B group vitamins

  • E54 Ascorbic acid deficiency

    Inclusion term(s):

    • Deficiency of vitamin C
    • Scurvy
  • E55 Vitamin D deficiency

  • E56 Other vitamin deficiencies

  • E58 Dietary calcium deficiency

  • E59 Dietary selenium deficiency

    Inclusion term(s):

    • Keshan disease
  • E60 Dietary zinc deficiency

  • E61 Deficiency of other nutrient elements

  • E63 Other nutritional deficiencies

  • E64 Sequelae of malnutrition and other nutritional deficiencies

    Note: This category is to be used to indicate conditions in categories E43, E44, E46, E50-E63 as the cause of sequelae, which are themselves classified elsewhere. The 'sequelae' include conditions specified as such; they also include the late effects of diseases classifiable to the above categories if the disease itself is no longer present


  • androgen insensitivity syndrome (E34.5-)
  • congenital adrenal hyperplasia (E25.0)
  • hemolytic anemias attributable to enzyme disorders (D55.-)
  • Marfan syndrome (Q87.4-)
  • 5-alpha-reductase deficiency (E29.1)


  • Ehlers-Danlos syndromes (Q79.6-)
  • E70 Disorders of aromatic amino-acid metabolism

  • E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism

  • E72 Other disorders of amino-acid metabolism

  • E73 Lactose intolerance

  • E74 Other disorders of carbohydrate metabolism

  • E75 Disorders of sphingolipid metabolism and other lipid storage disorders

  • E76 Disorders of glycosaminoglycan metabolism

  • E77 Disorders of glycoprotein metabolism

  • E78 Disorders of lipoprotein metabolism and other lipidemias

  • E79 Disorders of purine and pyrimidine metabolism

  • E80 Disorders of porphyrin and bilirubin metabolism

  • E83 Disorders of mineral metabolism

  • E84 Cystic fibrosis

  • E85 Amyloidosis

  • E86 Volume depletion

  • E87 Other disorders of fluid, electrolyte and acid-base balance

  • E88 Other and unspecified metabolic disorders

  • E89 Postprocedural endocrine and metabolic complications and disorders, not elsewhere classified